Science
Mechanism of Action
Chlorothymol exerts its primary action by compromising the structural integrity of microbial cell membranes in both bacteria and fungi. This disruption leads to cellular dysfunction and ultimately death, offering strong antiseptic and antimicrobial effects for localized application.
Research
Clinical Evidence
Low confidenceN/A
Key findings
- 01 An OTC skin cream containing Chlorothymol under semi-occlusion was considered a non-primary irritant and a non-primary sensitizer.
Transparency
Dusting Analysis
The Formula
Formulation
Stability
To prevent degradation, proper storage conditions are essential. It exhibits limited solubility in water, approximately 0.32 g/L.
Safety
Safety Profile
The Cosmetic Ingredient Review (CIR) Expert Panel has deemed Chlorothymol safe for use in cosmetics at concentrations up to 0.5%. However, due to its potential to irritate skin and eyes, and its capacity to seriously aggravate mucous membranes, careful formulation and usage precautions are advised.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Chlorothymol is a valuable antimicrobial and antiseptic ingredient for targeted skincare applications, provided it is precisely formulated within its established safety limits to mitigate irritation potential.
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References
Sources