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CHLOROFORM.

Avoid CAS 67-66-3 / SOLVENT

Chloroform, or Trichloromethane, is a volatile organic solvent historically recognized for its anesthetic properties. It is strictly prohibited in cosmetics due to significant risks of systemic toxicity and potential carcinogenicity.

Science

As a potent central nervous system depressant, chloroform's primary biological action is not skin-specific. Its mechanism for delivering topical cosmetic benefits is non-existent, making it irrelevant for skincare applications.


Research

Low confidence
Effective range N/A
Optimal

N/A


Transparency

Not commonly dusted

Not an approved cosmetic ingredient, therefore dusting analysis is not applicable.


The Formula

Solubility
Oil
Optimal pH N/A
0 7 14

Stability

Highly unstable, degrading in light and air to form hazardous byproducts like phosgene and hydrochloric acid.

Conflicts

  • strong bases
  • strong acids
  • certain metals

Safety

CIR Status
Prohibited in cosmetic formulations by major regulatory bodies, including the FDA and EU SCCS, due to severe safety concerns.
Max tested
0%
Pregnancy
Caution
Sensitization risk High

Classified as a probable human carcinogen and hepatotoxin. Demonstrates significant dermal absorption, posing systemic health risks even with topical exposure.


Your Skin

No Normal
No Dry
No Oily
No Sensitive
Irritancy High
Comedogenicity Unknown

Our Assessment

Avoid

Due to severe toxicity, potential carcinogenicity, and confirmed systemic absorption, chloroform must be unequivocally avoided in all cosmetic formulations.


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