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Moumoujus

CHLOROACETIC ACID.

Avoid CAS 79-11-8 / KERATOLYTIC

Chloroacetic Acid is a potent keratolytic primarily used in targeted dermatological treatments for various skin lesions, acting at high concentrations (e.g., 80%). It functions by disrupting cellular protein structures.

Summary

Keratolytic pH adjuster Exfoliant

Science

Mechanism of Action

As a strong keratolytic, it induces cell necrosis and shedding of the outermost skin layer by disrupting protein structures and interfering with cellular energy production.

Research

Clinical Evidence

High confidence
Effective range 80–80%
Optimal

80%

Key findings

  1. 01 Effective for warts, calluses, skin tags, molluscum contagiosum, keratoses, and certain skin cancers by causing cellular necrosis.

Transparency

Dusting Analysis

Not commonly dusted

Its extreme corrosivity and toxicity make it unsuitable for any form of general cosmetic application or airborne exposure.

The Formula

Formulation

Solubility
Water
Optimal pH N/A
0 7 14

Stability

A strong acid (pKa 2.86), stable yet deliquescent, forming highly acidic solutions typically below pH 1 at high concentrations.

Conflicts

  • Strong bases
  • Alkalis
  • Most common metals
  • Strong oxidizing agents
  • Amines
  • Systemic retinoids
  • Skin-drying/sensitizing drugs

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk High

Highly toxic and corrosive by all exposure routes, causing severe irritation and burns. Exposure to >6% body surface area can be fatal; banned as a food additive and classified as a hazardous substance.

Your Skin

Skin Compatibility

No Normal
No Dry
No Oily
No Sensitive
Irritancy High
Comedogenicity Unknown

Our Assessment

Verdict

Avoid

Due to its extreme toxicity, corrosivity, and high irritation potential, this ingredient is unsuitable for general cosmetic use and is strictly limited to controlled medical applications.

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