Science
Mechanism of Action
It targets the structural integrity of the dermal matrix by inhibiting Matrix Metalloproteinase-1 (MMP-1) and MMP-9, the enzymes primarily responsible for breaking down collagen. Additionally, it mitigates UVB-induced cellular stress by reducing apoptosis and suppressing inflammatory markers like IL-2.
Research
Clinical Evidence
High confidence0.1%
Key findings
- 01 A 12-week double-blind, placebo-controlled trial (n=23) demonstrated that a 0.1% concentration significantly improved skin roughness and wrinkle depth through the suppression of collagen-degrading enzymes.
Transparency
Dusting Analysis
Because this extract is effective at a very low 0.1% concentration, brands may list it at negligible amounts (e.g., 0.001%) to claim anti-aging benefits without providing the functional dose validated in clinical research.
The Formula
Formulation
Stability
Highly heat-sensitive due to the unsaturated lipid profile; must be incorporated during the cool-down phase below 40°C. Exhibits amphiphilic properties but requires an oil-phase carrier for stability.
Synergies
- Broad-spectrum UV filters
- Vitamin E
- Squalane
Conflicts
- Strong oxidizing agents
- Formulas with pH lower than 4.0 or higher than 8.0
- Sustained high-heat processing
Safety
Safety Profile
Clinically validated under KFDA safety guidelines; demonstrated zero adverse reactions or irritation in human patch testing at functional levels.
Your Skin
Skin Compatibility
Our Assessment
Verdict
A potent, low-dose biotech active that effectively halts collagen breakdown and provides measurable wrinkle reduction when formulated correctly.
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