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CHLAMYDOMONAS R-(OLIGOPEPTIDE-91 SH-POLYPEPTIDE-11 SH-POLYPEPTIDE-1 SH-POLYPEPTIDE-11).

Valuable / SKIN CONDITIONING, VISCOSITY CONTROLLING

A cutting-edge recombinant fusion protein complex that merges green algae biotechnology with advanced neuro-peptide engineering. This multi-functional complex is designed to target both facial muscle micro-contractions and the fundamental structural integrity of the dermis.

Neuro-cosmetic muscle relaxant Dermal remodeling growth factor Collagen synthesis stimulant Viscosity modifier

Science

This complex operates via a dual-action pathway: Oligopeptide-91 functions as a neuro-cosmetic agent that targets the SNARE complex to inhibit acetylcholine release, effectively relaxing expression lines with a Botox-like mechanism. Simultaneously, sh-Polypeptide-1 (bFGF) and sh-Polypeptide-11 (aFGF) act as bioactive growth factors that stimulate fibroblast proliferation, accelerating the synthesis of essential collagen, elastin, and hyaluronic acid.


Research

High confidence
Effective range 0.5–5%
Optimal

0.5%

Key findings

  1. 01 Clinical evaluation of a 0.5% concentration showed a measurable decrease in the depth of periorbital and forehead wrinkles alongside improved skin elasticity after 28 days of consistent use.
  2. 02 In-vivo analysis of the concentrated 5% raw material demonstrated significant enhancement in Type I collagen production and fibroblast cellular activity compared to untreated controls.

Transparency

Commonly dusted
Min. effective
0.5%
Red flag below
0.05%

Due to the high cost of this recombinant protein complex, it is frequently used at 'label claim' concentrations far below the 0.5% clinical threshold. Formulations containing less than 0.1% may not provide the advertised neuro-relaxing or regenerative benefits.


The Formula

Solubility
Water
Optimal pH 5.5 – 7.5
0 7 14

Stability

The complex is highly thermolabile; it must be incorporated during the cool-down phase at temperatures not exceeding 40°C to maintain protein folding and biological activity.

Synergies

  • Hyaluronic Acid
  • Non-proteolytic Peptides
  • Antioxidants

Conflicts

  • Proteolytic enzymes (Papain, Bromelain)
  • Strong acids (pH < 4.0)
  • Strong bases (pH > 8.5)
  • High heat (> 45°C)

Safety

CIR Status
Not reviewed
Pregnancy
Safe
Sensitization risk Low

While not formally reviewed by the CIR, it is categorized as a safe skin conditioning agent in the EU. Its peptide structure is generally well-tolerated by the skin's biological systems.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Valuable

An elite, scientifically-backed fusion protein that delivers sophisticated wrinkle-relaxing and skin-densifying results when formulated at the correct clinical threshold.


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References