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CHITOSAN LACTATE.

Valuable CAS 66267-50-6 / FILM FORMING, HAIR FIXING

A sophisticated, water-soluble derivative of chitin that combines the regenerative properties of polysaccharides with the gentle exfoliation of lactic acid. This cationic ingredient creates a breathable, protective matrix on the skin's surface, excelling at both deep hydration and microbial defense.

Film-forming Humectant Antimicrobial Penetration Enhancer Skin Conditioning

Science

As a cationic (positively charged) molecule, Chitosan Lactate anchors to the negatively charged surface of skin cells and bacteria through electrostatic attraction. It functions as a biocompatible penetration enhancer by temporarily adjusting epidermal tight junctions to allow active ingredients deeper access, while simultaneously forming a semi-permeable film that locks in moisture and shields against environmental pollutants.


Research

High confidence
Effective range 0.02–2%
Optimal

1.5%

Key findings

  1. 01 Achieved significant bactericidal reduction (1-5 log cycles) against S. aureus and E. coli within 60 minutes.
  2. 02 Established a protective biological barrier that significantly reduced transepidermal water loss and enhanced skin resilience.

Transparency

Commonly dusted
Min. effective
0.1%
Red flag below
0.05%

While Chitosan Lactate shows antimicrobial properties as low as 0.02%, its primary benefits for barrier repair and film-forming require concentrations above 0.5%. Formulations using 'trace amounts' for marketing claims likely miss the ingredient's structural skin-conditioning potential.


The Formula

Solubility
Water
Optimal pH 4 – 6.5
0 7 14

Stability

Maintains excellent clarity in acidic to neutral aqueous solutions; however, the ingredient may precipitate if the pH exceeds 7.0 due to deprotonation.

Synergies

  • Quercetin
  • Hyaluronic Acid
  • Glycerin
  • Antioxidants

Conflicts

  • Sodium Lauryl Sulfate
  • Carbomer
  • Polyacrylic Acid
  • Highly anionic thickeners
  • Concentrated electrolytes

Safety

CIR Status
Not specifically reviewed (Parent compound Chitosan is FDA GRAS)
Max tested
10%
Pregnancy
Safe
Sensitization risk Low

Lactic acid salts are generally cleared for leave-on use up to 10% when formulated at a pH of 3.5 or higher.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Valuable

An exceptional multifunctional ingredient for precision skincare, offering unique film-forming and delivery-enhancing properties with a high safety profile.


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