Science
Mechanism of Action
This ingredient functions as a signaling powerhouse by delivering a concentrated mixture of amino acids and growth factors (including those from the amnion and yolk sac) directly to skin cells. It modulates gene expression to prioritize the synthesis of Type I collagen and elastin while simultaneously inhibiting hyaluronidase and elastase—the enzymes responsible for degrading the skin's natural moisture and elasticity.
Research
Clinical Evidence
High confidence3%
Key findings
- 01 Demonstrated a 150% increase in Type I collagen synthesis and significantly accelerated the proliferation rate of fibroblasts.
- 02 Identified 217 distinct bio-active factors including essential growth factors and amino acids.
- 03 Confirmed significant inhibitory action against enzymes that degrade hyaluronic acid and elastin fibers.
Transparency
Dusting Analysis
Due to its high manufacturing cost and 'high-tech' marketing appeal, this ingredient is frequently included at sub-clinical levels. Concentrations below 1% are unlikely to trigger the fibroblast proliferation and collagen synthesis observed in technical evaluations.
The Formula
Formulation
Stability
Highly thermolabile; it must be incorporated during the cooling phase of production at temperatures below 40°C to prevent denaturation of the protein-rich signaling molecules.
Synergies
- Peptides
- Hyaluronic Acid
- Niacinamide
Conflicts
- High heat (>40°C)
- Low pH exfoliants (pH < 4.0)
- Strong alkaline environments (pH > 8.0)
- High concentrations of ethanol
Safety
Safety Profile
Extensively validated through an eight-tier safety battery, including RIPT, 3D eye and skin irritation models, and chromosomal abnormality testing. It is confirmed to be non-sensitizing and non-irritating.
Your Skin
Skin Compatibility
Our Assessment
Verdict
An exceptional multi-functional active that provides statistically significant improvements in skin density and enzymatic protection when formulated at 1% or higher.
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References
Sources