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CETYLOXY DIMETHICONE.

Valuable / SKIN CONDITIONING, SKIN CONDITIONING - EMOLLIENT

An advanced substituted silicone polymer that functions as a high-performance emollient and protective barrier agent. By integrating cetyloxy groups, it achieves superior lipophilicity compared to standard dimethicone, resulting in a refined, silky texture and enhanced skin-barrier integration.

Emollient Skin Conditioning Agent Occlusive Barrier Protector

Science

This ingredient establishes a breathable, viscoelastic film on the skin's surface, acting as a hydrophobic shield to significantly reduce transepidermal water loss (TEWL). Its specific molecular structure allows it to effectively fill intercellular gaps within the stratum corneum, reinforcing the skin's natural defense against external irritants while maintaining optimal gas exchange.


Research

High confidence
Effective range 5–15%
Optimal

15%

Key findings

  1. 01 A 2021 CIR Safety Assessment confirmed that concentrations up to 15% are non-irritating and exhibit zero significant dermal absorption.
  2. 02 Human Repeated Insult Patch Tests (HRIPT) at 5.0% concentrations demonstrated no potential for dermal sensitization or allergic reaction.

Transparency

Not commonly dusted
Min. effective
1%
Red flag below
0.5%

As a functional texture enhancer and barrier agent, it is typically used at effective concentrations to achieve the desired skin feel; however, concentrations below 1% may indicate it is being used primarily for label claims rather than significant occlusive benefits.


The Formula

Solubility
Oil
Optimal pH 4 – 8.5
0 7 14

Stability

Exhibits exceptional thermal stability, maintaining structural integrity in processes involving heat up to 100°C.

Synergies

  • Mineral UV filters
  • Lipophilic active delivery systems
  • Ceramides

Conflicts

  • Strong acids
  • Strong oxidizing agents

Safety

CIR Status
Safe as used
Max tested
15%
Pregnancy
Safe
Sensitization risk Low

Its large molecular weight prevents systemic absorption, making it biologically inert and safe for long-term topical use.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Valuable

A highly stable, non-sensitizing barrier ingredient that provides superior moisture retention and a luxury sensory profile for all skin types.


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