Science
Mechanism of Action
This ingredient functions by creating a vapor-permeable, breathable film across the epidermis. This non-occlusive barrier significantly reduces transepidermal water loss (TEWL) while simultaneously acting as a 'detackifier' to eliminate the sticky sensation often found in high-moisture aqueous formulas, enhancing overall product spreadability.
Research
Clinical Evidence
High confidence5%
Key findings
- 01 The 2014 CIR Final Report confirmed systemic safety and lack of sensitization across a broad concentration range up to 5.6%.
- 02 Hydrolytic stability testing in 2019 demonstrated that a 5% concentration provides superior resistance to degradation across varying pH levels for up to 165 days.
Transparency
Dusting Analysis
While safe at very low levels, concentrations below 1% may be utilized purely for marketing claims or minor texture adjustment rather than achieving the robust barrier-protective and stabilizing benefits seen in clinical evaluations.
The Formula
Formulation
Stability
Optimal stability is maintained within a pH range of 5.5 to 8.5. It is heat-sensitive and should not be processed above 50°C (122°F) to avoid polymer chain degradation.
Synergies
- Hyaluronic acid
- Glycerin
- Other dimethicone derivatives
Conflicts
- Strong oxidizing agents
- Extreme pH environments (<4.0 or >9.0)
- High heat manufacturing processes
Safety
Safety Profile
Due to its high molecular weight (>10,000 Daltons), this ingredient is not absorbed into the bloodstream, making it safe for topical use. Human patch tests at standard usage levels show no primary irritation.
Your Skin
Skin Compatibility
Our Assessment
Verdict
An excellent textural and barrier-supporting agent that provides a sophisticated, non-greasy finish for all skin types.
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References
Sources