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CETYL GLYCOL.

Valuable CAS 6920-24-7 / HAIR CONDITIONING, SKIN CONDITIONING, SKIN CONDITIONING - EMOLLIENT, VISCOSITY CONTROLLING

A high-performance fatty diol that acts as both a moisture-locking emollient and a strategic preservative booster. Its 16-carbon structure provides a velvety skin feel while enhancing the structural integrity and antimicrobial resilience of complex formulas.

Emollient Skin conditioning agent Viscosity regulator Preservative booster Co-emulsifier

Science

The long-chain alkyl structure creates a breathable occlusive film that prevents trans-epidermal water loss (TEWL) and softens the stratum corneum. Simultaneously, its vicinal diol configuration exhibits surface-active properties that disrupt microbial cell membranes, allowing it to synergistically amplify the efficacy of traditional preservatives.


Research

High confidence
Effective range 0.25–5%
Optimal

2%

Key findings

  1. 01 Clinical evaluations established a 5% threshold for sensitization testing, noting safety at 1% for sensitive populations.
  2. 02 Research indicates optimized antimicrobial synergy occurs between 0.25% and 2.0% through membrane permeability enhancement.
  3. 03 Safety assessments of related 16-carbon alcohols at 8.4% demonstrated no evidence of irritation in standardized patch testing.

Transparency

Not commonly dusted
Min. effective
0.25%
Red flag below
0.1%

While rarely used as a 'marketing' ingredient, concentrations below 0.25% may fail to provide the functional antimicrobial boosting or texture-modifying benefits the ingredient is selected for.


The Formula

Solubility
Oil
Optimal pH 3 – 11
0 7 14

Stability

A waxy solid with a melting point of 68-72°C; requires heating and integration into the oil phase. Exhibits exceptional stability across a broad pH spectrum but may crystallize in cold-process systems if solubility limits are exceeded.

Synergies

  • Preservative systems
  • Co-emulsifiers
  • Lipophilic active delivery systems

Conflicts

  • Strong oxidizing agents
  • Highly polar aqueous systems without proper co-solvents

Safety

CIR Status
Safe as used
Max tested
5%
Pregnancy
Safe
Sensitization risk Low

Non-toxic and non-irritating at standard formulation levels. Sensitization is only typically observed when exceeding the 5% maximum use concentration.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Valuable

An essential multifunctional stabilizer that improves both the skin-feel and the safety profile of high-performance skincare.


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