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CETYL ETHYLHEXANOATE.

Valuable CAS 59130-69-7 / SKIN CONDITIONING - EMOLLIENT

A high-performance synthetic ester that serves as a lightweight emollient to impart a silky, non-greasy finish to skincare formulations. It is valued for its ability to enhance product spreadability while reinforcing the skin's natural moisture barrier.

Emollient Occlusive Skin Conditioner Texture Enhancer Penetration Enhancer

Science

It functions as an occlusive agent by forming a thin, water-repellent film on the stratum corneum, which effectively traps moisture and reduces transepidermal water loss (TEWL). Beyond its barrier functions, it acts as a penetration enhancer by improving the solubility of other active ingredients, thereby increasing their permeation into the skin.


Research

High confidence
Effective range 1–77.3%
Optimal

N/A

Key findings

  1. 01 Clinical assessments indicate that a 1% concentration significantly improves the permeation rate of lipid-soluble substances via enhanced solubility.
  2. 02 A 48-hour patch test on 50 subjects showed that while undiluted (100%) concentrations can be mildly irritating to a subset of users, diluted cosmetic applications remain highly tolerable.

Transparency

Not commonly dusted

As a texture-enhancing emollient and solvent, it is typically used as a functional base or carrier rather than a 'hero' active, making 'dusting' (using sub-clinical amounts for marketing) less applicable.


The Formula

Solubility
Oil
Optimal pH N/A
0 7 14

Stability

Demonstrates excellent stability against oxidation and hydrolysis across a broad range of temperatures and pH levels common in skincare.

Synergies

  • Lipophilic active ingredients
  • UV filters
  • Pigments

Safety

CIR Status
Safe as used
Max tested
77.3%
Pregnancy
Safe
Sensitization risk Low

The ingredient is considered safe in current cosmetic practices, with concentrations reaching up to 77.3% in rinse-off products and 52% in leave-on lip formulations.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Valuable

An exceptionally stable and versatile emollient that optimizes formula texture and enhances the delivery of co-formulated active ingredients.


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References