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CETYL DIMETHYLBUTYL ETHER.

Valuable CAS 185143-68-4 / SKIN CONDITIONING

A high-performance synthetic fatty ether that functions as a lightweight emollient and specialized solvent. It is engineered to provide a breathable moisture barrier while effectively solubilizing complex lipids and pigments without the oxidative instability or greasy residue of traditional plant oils.

Emollient Solvent Skin-conditioning agent Cleansing enhancer

Science

This non-polar molecule forms a thin, breathable occlusive film on the skin's surface, which significantly reduces trans-epidermal water loss (TEWL) and enhances the suppleness of the stratum corneum. In cleansing applications, its molecular structure allows it to rapidly dissolve sebum and long-wear cosmetic waxes, facilitating a deep cleanse while maintaining the integrity of the skin's natural lipid barrier.


Research

High confidence
Effective range 1–19.3%
Optimal

19.3%

Key findings

  1. 01 A 2022 HRIPT study involving 99 subjects confirmed zero evidence of dermal irritation or sensitization at concentrations up to 19.3%.
  2. 02 In vitro dermal penetration analysis indicates minimal systemic absorption (approximately 0.3%), validating its safety for topical application.

Transparency

Not commonly dusted
Min. effective
1%
Red flag below
0.1%

As a functional solvent and emollient, this ingredient is typically used at meaningful percentages to achieve desired texture and cleansing performance; it is rarely used in 'dusting' amounts for marketing purposes.


The Formula

Solubility
Oil
Optimal pH 3 – 11
0 7 14

Stability

Exceptional stability profile; the ether linkage is molecularly resistant to both hydrolysis and oxidation, maintaining performance across extreme pH levels and temperature fluctuations.

Synergies

  • Lipophilic pigments
  • Mineral UV filters
  • Non-polar surfactants

Conflicts

  • Requires high-shear emulsification for aqueous systems

Safety

CIR Status
Safe as used
Max tested
19.3%
Pregnancy
Safe
Sensitization risk Low

Verified as non-mutagenic and non-genotoxic. Its high molecular weight prevents significant skin penetration, ensuring it remains on the surface where it is needed.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Valuable

An elite, ultra-stable emollient and solvent that offers superior makeup removal and skin softening with a high safety profile and zero greasy after-feel.


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