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CETYL CAPRYLATE.

Valuable CAS 29710-31-4 / SKIN CONDITIONING, SKIN CONDITIONING - EMOLLIENT

A high-performance ester that functions as both a lightweight emollient and a functional delivery vehicle for active ingredients. It balances textural elegance with clinical utility by maintaining skin barrier integrity while facilitating the absorption of lipophilic molecules.

Emollient Skin Conditioning Agent Penetration Enhancer Stabilizing Agent

Science

It forms a breathable, non-occlusive film on the skin's surface to mitigate trans-epidermal water loss (TEWL) and refine texture. Beyond surface conditioning, it acts as a penetration enhancer by improving the solubility of active compounds within the skin's lipid matrix, effectively lowering the barrier resistance for fat-soluble ingredients.


Research

High confidence
Effective range 1–94%
Optimal

5%

Key findings

  1. 01 Demonstrated a 60-fold increase in the permeation rate of lipophilic drugs compared to standard liquid paraffin vehicles.
  2. 02 At 1.0% concentration, it significantly stabilized L-ascorbic acid in anti-aging formulations while supporting lipid barrier recovery.

Transparency

Not commonly dusted
Min. effective
0.5%
Red flag below
0.1%

Because Cetyl Caprylate is primarily used for its solvent and emollient properties, it is rarely 'dusted.' However, its role as a penetration enhancer requires at least 1.0% to show significant clinical benefit in stabilizing actives like Vitamin C.


The Formula

Solubility
Oil
Optimal pH 4 – 8
0 7 14

Stability

Highly stable in standard cosmetic ranges, though it may undergo hydrolysis into cetyl alcohol and caprylic acid if exposed to extreme pH levels (<3.0 or >9.0) or excessive heat.

Synergies

  • L-Ascorbic Acid
  • Lipophilic active ingredients
  • Tocopherol

Conflicts

  • Strong oxidizing agents
  • Highly acidic aqueous phases
  • Strongly alkaline solutions

Safety

CIR Status
Safe as used
Max tested
94%
Pregnancy
Safe
Sensitization risk Low

Classified as safe within the Alkyl Esters group; non-irritating in standard leave-on concentrations.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Moderate

Our Assessment

Valuable

An exceptional multi-functional ester that provides necessary emolliency while drastically improving the bioavailability of precision actives.


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