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CETYL AMODIMETHICONE.

Valuable / HAIR CONDITIONING, SKIN CONDITIONING

An advanced, multifunctional alkyl-amino-modified silicone that fuses the emolliency of cetyl lipids with the film-forming tenacity of amodimethicone. This hybrid polymer creates a breathable, silk-like barrier on the skin's surface, enhancing both hydration retention and the wear-time of cosmetic formulations.

Emollient Skin conditioning agent Film former Barrier protectant

Science

The molecule utilizes a dual-action mechanism: its C16 cetyl group provides lipid-like nourishment and water resistance, while its amino groups carry a cationic charge at skin-neutral pH. This allows the ingredient to electrostatically bond to the skin's naturally negative surface proteins, forming a substantive, protective lattice that prevents transepidermal water loss (TEWL) without occluding pores.


Research

High confidence
Effective range 1–15%
Optimal

5%

Key findings

  1. 01 Clinical assessments by the Cosmetic Ingredient Review indicate that substituted-methicone polymers at concentrations up to 5% show zero significant dermal irritation and no systemic absorption due to their high molecular weight.

Transparency

Not commonly dusted
Min. effective
1%
Red flag below
0.5%

While often used as a secondary texture enhancer at low levels, true barrier support and long-wear benefits require concentrations of at least 1-2%. Formulations using it below 0.5% likely include it for marketing claims rather than functional performance.


The Formula

Solubility
Oil
Optimal pH 4 – 8
0 7 14

Stability

Exhibits superior stability in anhydrous systems and oil-in-water emulsions; substantivity is maximized between pH 4.5 and 6.5.

Synergies

  • Lipophilic sunscreens
  • Mineral pigments
  • Barrier lipids

Conflicts

  • Strong anionic surfactants
  • Strong oxidizing agents

Safety

CIR Status
Safe as used
Max tested
15%
Pregnancy
Safe
Sensitization risk Low

Large molecular size ensures the ingredient remains on the skin surface with no risk of dermal penetration.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Valuable

An exceptional ingredient for achieving long-lasting skin protection and a refined finish without the heaviness of traditional silicones.


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