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CETETH-8 PHOSPHATE.

Valuable CAS 50643-20-4 / CLEANSING, SURFACTANT - CLEANSING, SURFACTANT - EMULSIFYING

An advanced anionic phosphate ester that serves as a high-performance emulsifier and texture stabilizer. It is specifically engineered to bridge the gap between oil and water phases while simultaneously facilitating the delivery of active molecules into the skin's deeper layers.

Emulsifying Surfactant Penetration Enhancer Cleansing Agent

Science

It functions as an amphiphilic surfactant that reduces interfacial tension to create robust oil-in-water emulsions. Beyond stabilization, the phosphate group possesses a unique affinity for the skin's lipid matrix, temporarily rearranging the stratum corneum's structural organization to act as a penetration enhancer for targeted active ingredients.


Research

High confidence
Effective range 1–25%
Optimal

5%

Key findings

  1. 01 Clinical evaluations and patent data demonstrate that concentrations within the 1-25% range significantly accelerate the absorption of active ingredients, reducing penetration lag times to under 60 minutes.

Transparency

Not commonly dusted
Min. effective
1%
Red flag below
0.5%

As a functional emulsifier and penetration enhancer, levels below 1.0% are often insufficient to provide the structural stability or the delivery-boosting benefits for which this ingredient is valued.


The Formula

Solubility
Both
Optimal pH 4 – 6.5
0 7 14

Stability

Maintains peak performance in slightly acidic environments; exceptionally effective at stabilizing high-viscosity formulations with heavy oil loads.

Synergies

  • Phospholipids
  • Hydrophobic active ingredients
  • Mineral UV filters

Conflicts

  • Cationic surfactants
  • Polyquaterniums
  • Heavy metal ions
  • Quaternary ammonium compounds

Safety

CIR Status
Safe as used
Max tested
8.3%
Pregnancy
Safe
Sensitization risk Low

Safe for topical use when formulated to be non-irritating; the 8.3% threshold is the established safety ceiling for leave-on applications.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Valuable

A sophisticated functional ingredient that optimizes formula stability while enhancing the bioavailability of therapeutic actives.


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