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CETETH-23.

Valuable CAS 9004-95-9 / CLEANSING, SURFACTANT - CLEANSING, SURFACTANT - EMULSIFYING

A high-performance nonionic polyoxyethylene ether derived from cetyl alcohol, primarily utilized as a sophisticated oil-in-water emulsifier. It is engineered to create exceptionally stable, elegant textures in pharmaceutical-grade skincare while ensuring the seamless integration of water and oil phases.

Surfactant Cleansing Agent Emulsifying Stabilizer

Science

As a high HLB (Hydrophilic-Lipophilic Balance) surfactant with a value of approximately 18.0, Ceteth-23 functions by lowering the interfacial tension between disparate phases. This allows it to stabilize emulsions and facilitate the removal of lipid-based impurities from the skin surface during cleansing by making them water-miscible.


Research

High confidence
Effective range 2–10%
Optimal

5%

Key findings

  1. 01 Validated as a pharmaceutical-grade stabilizer (Setomacrogol 1000) that maintains emulsion integrity without triggering skin sensitization.
  2. 02 Established as a safe maximum threshold for leave-on applications within a comprehensive safety assessment of alkyl PEG ethers.

Transparency

Not commonly dusted
Min. effective
1%
Red flag below
0.5%

Because Ceteth-23 is a functional emulsifier rather than an active treatment, 'dusting' is less of a concern; however, concentrations below 1% in heavy emulsions may indicate insufficient stabilization or purely symbolic inclusion.


The Formula

Solubility
Water
Optimal pH 3 – 11
0 7 14

Stability

Demonstrates remarkable resistance to hydrolysis and remains stable across an expansive pH spectrum. It is highly versatile, maintaining compatibility with anionic, cationic, and nonionic surfactant systems.

Synergies

  • Cetyl Alcohol
  • Low HLB emulsifiers
  • Glycerin

Conflicts

  • Strong oxidizing agents
  • High concentrations of phenolic compounds

Safety

CIR Status
Safe as used
Max tested
10%
Pregnancy
Safe
Sensitization risk Low

Safety is contingent upon the removal of manufacturing by-products like 1,4-dioxane and ethylene oxide; pharmaceutical-grade sources are preferred for precision skincare.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Valuable

A reliable and inert pharmaceutical-grade stabilizer that ensures product integrity and texture without compromising skin barrier health.


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