Science
Mechanism of Action
As a lipophilic agent with a low Hydrophilic-Lipophilic Balance (HLB) of approximately 5.3, Ceteth-2 reduces interfacial tension to stabilize water-in-oil emulsions. It works by forming a robust interfacial film around oil droplets, preventing coalescence and ensuring a uniform distribution of ingredients.
Research
Clinical Evidence
High confidence3%
Key findings
- 01 Clinical patch testing at a 3.0% concentration confirmed the ingredient is non-irritating to intact human skin.
- 02 Research indicates dose-dependent irritation at concentrations exceeding 5.0%, particularly in undiluted forms.
- 03 Studies on abraded skin at 2.5% showed potential for irritation, emphasizing the importance of formula-specific irritation testing.
Transparency
Dusting Analysis
Ceteth-2 is a functional texture-builder rather than an 'active' ingredient marketed for results; therefore, it is rarely 'dusted' for marketing claims. Its presence is typically dictated by the structural requirements of the emulsion.
The Formula
Formulation
Stability
Highly resilient waxy solid that remains stable in both extreme acidic and alkaline environments. It has a melting point between 27-35°C.
Synergies
- Co-emulsifiers
- Oil-soluble UV filters
Conflicts
- Strong oxidizing agents
- Specific anionic surfactants that may form complexes
Safety
Safety Profile
Safe for intact skin up to 10.0%. It should be avoided on severely damaged or burned skin due to potential risks associated with PEG-related nephrotoxicity in compromised barriers.
Your Skin
Skin Compatibility
Our Assessment
Verdict
A reliable and pH-stable functional emulsifier best suited for dry and normal skin types in rich, barrier-focused formulations.
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References
Sources