Science
Mechanism of Action
As a non-ionic surfactant with an HLB value between 15.1 and 15.5, Ceteth-15 lowers the surface tension between disparate phases to create stable, uniform emulsions. Beyond its structural role, it facilitates the removal of lipid-based impurities during cleansing and can potentially enhance the dermal penetration of co-formulated active ingredients.
Research
Clinical Evidence
High confidence5%
Key findings
- 01 Concentrations of 1.35% were clinically validated as non-sensitizing in Repeat-Insult Patch Testing (RIPT).
- 02 Usage at 1.5% demonstrated minimal to no irritation in both short-term (4-day) and extended (21-day) patch trials.
- 03 Safety assessments indicate that while undiluted Ceteths can be dose-dependent irritants, they remain biocompatible when formulated below 10%.
Transparency
Dusting Analysis
Because Ceteth-15 is primarily a functional texturizer and emulsifier rather than a primary active, it is rarely 'dusted' for marketing purposes. It is typically included at necessary concentrations to ensure formula stability.
The Formula
Formulation
Stability
Exhibits robust chemical stability across a wide pH range due to its non-ionic nature. It is particularly resistant to acidic and alkaline environments.
Synergies
- Low-HLB emulsifiers
- Lipophilic active ingredients
- Humectants
Conflicts
- Strong oxidizing agents
- High electrolyte concentrations (may cause salting out)
- Extreme pH levels beyond 3-11 (hydrolysis risk)
Safety
Safety Profile
Manufacturers must adhere to strict purification standards to ensure residual 1,4-dioxane remains below 1 ppm.
Your Skin
Skin Compatibility
Our Assessment
Verdict
A highly stable and skin-compatible emulsifier that ensures formula integrity and improves the delivery of active ingredients.
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References
Sources