Science
Mechanism of Action
As an ethoxylated fatty alcohol, Ceteth-13 operates through an amphiphilic structure where its lipophilic cetyl group anchors in oils while its hydrophilic PEG-13 chain extends into the water phase. This action lowers surface tension, allowing for the creation of stable oil-in-water (O/W) emulsions and facilitating the gentle removal of lipids and debris during cleansing.
Research
Clinical Evidence
High confidence5%
Key findings
- 01 Clinical evaluation demonstrates high efficacy as an O/W emulsifier in microemulsions and stick formats, ensuring even distribution of active ingredients (US Patents 7,282,196; 5,800,804).
- 02 CIR safety assessments confirm the ingredient is non-sensitizing and non-irritating at concentrations up to 10% in topical applications.
Transparency
Dusting Analysis
As a functional excipient rather than a primary active, Ceteth-13 is rarely 'dusted' for marketing claims; however, levels below 0.1% may indicate insufficient concentrations for maintaining emulsion stability in high-lipid formulas.
The Formula
Formulation
Stability
Highly robust due to ether linkages that resist hydrolysis better than ester-based alternatives. It possesses an HLB value of approximately 13.8, ideal for O/W stabilization.
Synergies
- Lipophilic actives
- Mineral UV filters
- Humectants
Conflicts
- Strong oxidizing agents
- Extremely acidic environments (pH < 2)
Safety
Safety Profile
Manufacturers utilize vacuum stripping to ensure potential processing byproducts like 1,4-dioxane remain below 1 ppm for maximum purity.
Your Skin
Skin Compatibility
Our Assessment
Verdict
A reliable and skin-friendly structural component essential for creating stable, uniform, and cosmetically elegant emulsions.
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References
Sources