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CETEARYL GLUCOSIDE.

Valuable CAS 246159-33-1 / SURFACTANT - CLEANSING, SURFACTANT - EMULSIFYING

A sophisticated, plant-derived non-ionic emulsifier that bridges the gap between formulation stability and active skincare. Unlike traditional surfactants, it organizes into lamellar structures that mimic the skin’s own lipid architecture to provide both texture and hydration.

Emulsifying Surfactant Skin-conditioning Barrier-repair

Science

It functions by creating liquid crystal (lamellar) structures within an emulsion. These microscopic layers integrate with the stratum corneum's natural lipid bilayers, effectively reinforcing the skin barrier, preventing transepidermal water loss (TEWL), and facilitating a controlled release of active ingredients.


Research

High confidence
Effective range 1–7%
Optimal

1.5%

Key findings

  1. 01 An in vivo study utilizing a 5-7% concentration of a Cetearyl Alcohol/Glucoside blend demonstrated a 21.5% increase in skin hydration and a 9.9% reduction in TEWL after 8 hours.
  2. 02 Clinical evaluations at 1-1.5% confirm its ability to produce stable, non-greasy emulsions with a characteristic 'velvety' skin feel and enhanced spreadability.

Transparency

Not commonly dusted
Min. effective
1%
Red flag below
0.5%

As a primary emulsifier, it is rarely 'dusted' because a minimum threshold is required to maintain the structural integrity of the cream or lotion. Concentrations below 1% may indicate it is being used as a secondary surfactant rather than a barrier-mimicking chassis.


The Formula

Solubility
Both
Optimal pH 3 – 12
0 7 14

Stability

Exceptional stability across a wide pH spectrum. It is highly resistant to electrolytes and is typically incorporated into the oil phase at 70-80°C.

Synergies

  • Cetearyl Alcohol
  • Cationic surfactants
  • High-electrolyte actives

Conflicts

  • No major chemical incompatibilities reported

Safety

CIR Status
Safe as used
Max tested
5%
Pregnancy
Safe
Sensitization risk Low

The CIR Expert Panel considers it safe for leave-on products, especially when formulated to be non-irritating. It is non-sensitizing even at higher clinical concentrations.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Valuable

An excellent green-chemistry emulsifier that provides significant barrier-reinforcement benefits beyond its functional role in a formula.


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