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CETEARETH-80.

Valuable CAS 68439-49-6 / CLEANSING, SURFACTANT - CLEANSING

A high-performance non-ionic emulsifier and solubilizer characterized by its high molecular weight and exceptional water solubility. It is specifically utilized in precision skincare to stabilize complex oil-in-water systems and ensure the uniform distribution of hydrophobic active ingredients.

Surfactant Cleansing Agent Emulsifying Agent Solubilizer

Science

As a high HLB (18.5-18.7) surfactant, it reduces surface tension to bridge aqueous and lipid phases, effectively solubilizing fragrances and oils into clear solutions. On the skin, it creates a breathable, light occlusive barrier that preserves hydration while mitigating the potential irritation often associated with more aggressive cleansing agents.


Research

High confidence
Effective range 1.3–10%
Optimal

5%

Key findings

  1. 01 Evaluations by the CIR Expert Panel confirm the ingredient is non-toxic and exhibits minimal to no irritation within typical cosmetic use levels.
  2. 02 Comparative data shows that the high ethoxylation of Ceteareth-80 results in significantly lower skin irritation potential than lower molecular weight counterparts.

Transparency

Not commonly dusted
Min. effective
1%
Red flag below
0.5%

Because its primary role is structural stability and solubilization, it is rarely 'dusted' for marketing claims. However, if used below 1% in formulas containing high oil loads, it may indicate insufficient stabilization.


The Formula

Solubility
Water
Optimal pH 3 – 12
0 7 14

Stability

Exhibits robust thermal stability and remains effective across an extremely wide pH range; can stabilize formulations with oil phases up to 30%.

Synergies

  • Anionic surfactants
  • Cationic conditioning agents
  • Essential oils

Conflicts

  • Strong oxidizing agents

Safety

CIR Status
Safe as used
Max tested
10%
Pregnancy
Safe
Sensitization risk Low

While generally safe, it should not be applied to severely damaged or burned skin due to the absorption risk of PEG compounds. Industrial purity is strictly monitored for 1,4-dioxane levels.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Valuable

An essential formulation tool for creating stable, clear, and non-irritating aqueous delivery systems for oil-soluble actives.


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