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CETEARETH-40.

Valuable CAS 68439-49-6 / CLEANSING, SURFACTANT - CLEANSING

Ceteareth-40 is a high-performance, non-ionic surfactant and polyoxyethylene ether derived from cetearyl alcohol. It serves as a sophisticated emulsifying agent that ensures structural integrity in oil-in-water formulations while offering subtle emollient benefits.

Emulsifying Cleansing Solubilizing Surfactant

Science

As a high HLB (Hydrophilic-Lipophilic Balance) stabilizer, it reduces the interfacial tension between water and oil phases to create homogenous emulsions. Beyond stabilization, it forms a lightweight occlusive barrier that mitigates transepidermal water loss (TEWL) and acts as a surfactant to gently suspend surface impurities for efficient cleansing.


Research

High confidence
Effective range 1.3–10%
Optimal

5%

Key findings

  1. 01 Clinical evaluations conducted by the CIR Expert Panel across various concentrations (1.3-10%) demonstrate that Ceteareth compounds exhibit minimal to no irritation or sensitization in 4-day and 21-day patch testing.
  2. 02 Human clinical repeat-insult patch tests (HRIPT) on close molecular analogs confirmed a lack of sensitizing potential at concentrations up to 1.5%.

Transparency

Not commonly dusted
Min. effective
1%
Red flag below
0.5%

As a functional emulsifier, Ceteareth-40 is rarely 'dusted' for marketing purposes; its presence is typically dictated by the structural requirements of the formulation. However, concentrations below 0.5% in complex emulsions may indicate it is only being used as a secondary solubilizer rather than a primary stabilizer.


The Formula

Solubility
Water
Optimal pH 5 – 7
0 7 14

Stability

Exhibits exceptional stability in the presence of electrolytes and hard water. Maintains structural integrity across a broad temperature spectrum and is compatible with anionic and cationic systems.

Synergies

  • Anionic surfactants
  • Cationic conditioners
  • Non-ionic co-emulsifiers

Conflicts

  • Strong oxidizing agents
  • Highly acidic environments
  • Highly alkaline environments

Safety

CIR Status
Safe as used
Max tested
10%
Pregnancy
Safe
Sensitization risk Low

Safe for topical use on intact skin; however, caution is advised for application on severely damaged or broken skin barriers. Quality control must ensure 1,4-dioxane levels remain below 1 ppm.


Your Skin

Yes Normal
Yes Dry
Yes Oily
No Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Valuable

A highly reliable and versatile stabilizer essential for creating elegant, high-viscosity skincare textures with a proven safety profile.


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