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CETEARETH-15.

Valuable CAS 68439-49-6 / SURFACTANT - CLEANSING, SURFACTANT - EMULSIFYING

A high-performance non-ionic surfactant and emulsifier derived from cetearyl alcohol and ethylene oxide. It serves as a structural stabilizer in precision skincare, ensuring the cohesive integration of oil and water phases into smooth, uniform emulsions.

Emulsifying Surfactant Cleansing Penetration Enhancer

Science

By reducing interfacial tension, Ceteareth-15 facilitates the creation of stable oil-in-water (O/W) emulsions. Beyond its primary structural role, its ethoxylated nature allows it to act as a penetration enhancer, temporarily modifying the skin's lipid barrier to improve the delivery of neighboring active molecules.


Research

High confidence
Effective range 1–10%
Optimal

1.5%

Key findings

  1. 01 Human Repeat-Insult Patch Tests (HRIPT) at 1.35% confirmed the ingredient as a non-sensitizer.
  2. 02 Patch testing over 4-day and 21-day periods at 1.5% concentration demonstrated minimal to zero irritation potential.
  3. 03 Dermal exposure trials at concentrations as high as 10% showed only minimal irritation in animal models.

Transparency

Not commonly dusted
Min. effective
0.5%
Red flag below
0.1%

As a functional emulsifier, Ceteareth-15 is rarely 'dusted' for marketing purposes. It is typically included at levels between 1% and 5% to achieve formula stability; concentrations below 0.5% may indicate a lack of significant structural contribution.


The Formula

Solubility
Both
Optimal pH 5.5 – 8.5
0 7 14

Stability

Possesses a broad chemical stability range (pH 3.0–12.0) and high electrolyte tolerance, though emulsion integrity is peak within physiological skin pH levels.

Synergies

  • Lipophilic actives
  • Electrolyte-rich botanical extracts

Conflicts

  • Strong oxidizing agents
  • Damaged or compromised skin barriers

Safety

CIR Status
Safe as used
Max tested
10%
Pregnancy
Safe
Sensitization risk Low

While safe for general use, it must not be applied to broken or severely damaged skin (such as burns) due to the risk of systemic absorption of PEG-based components. Purity standards require monitoring for 1,4-dioxane.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Valuable

A reliable, non-irritating stabilizer that bridges the gap between texture and ingredient delivery in sophisticated emulsions.


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References