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CETEARETH-100.

Valuable CAS 68439-49-6 / CLEANSING, SURFACTANT - CLEANSING

A high-performance non-ionic emulsifier and stabilizer used to create sophisticated oil-in-water textures. This waxy solid ensures that complex skincare formulas remain homogenous while providing a subtle protective moisture seal on the skin's surface.

surfactant emulsifying solubilizing texture enhancer

Science

By lowering the interfacial tension between aqueous and lipid phases, Ceteareth-100 enables the formation of stable emulsions. Its high Hydrophilic-Lipophilic Balance (HLB) of 18.5 makes it particularly effective at solubilizing stubborn ingredients, while its ability to form a breathable occlusive film helps prevent transepidermal water loss (TEWL).


Research

High confidence
Effective range 1.3–10%
Optimal

5%

Key findings

  1. 01 Clinical evaluations published in the Journal of Cosmetic Science (2014) demonstrate that concentrations between 1.3% and 10% significantly enhance skin hydration and support barrier repair, notably in compromised skin environments.

Transparency

Not commonly dusted
Min. effective
1.3%
Red flag below
0.5%

While often used as a simple texture enhancer at low levels, clinical data suggests that a minimum of 1.3% is required to actively contribute to skin barrier repair and 24-hour hydration benefits.


The Formula

Solubility
Water
Optimal pH 4 – 9
0 7 14

Stability

Maintains integrity across a wide pH range and in the presence of hard water; however, high electrolyte or salt concentrations can destabilize the emulsion by lowering the cloud point.

Synergies

  • Poorly water-soluble actives
  • Cold-process emulsifiers
  • Lipophilic skin conditioners

Conflicts

  • Phenolic compounds
  • High concentrations of electrolytes
  • Strong oxidizing agents

Safety

CIR Status
Safe as used
Max tested
10%
Pregnancy
Safe
Sensitization risk Low

Safe for general use, though the CIR advises against application on severely damaged or burnt skin due to potential systemic absorption of PEG components. Raw material purity must meet strict <1 ppm 1,4-dioxane standards.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Valuable

A robust and versatile stabilizer that offers legitimate barrier-support benefits when used at clinical concentrations.


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References