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CETEARAMIDOETHYLDIETHONIUM SUCCINOYL HYDROLYZED KERATIN.

Valuable / HAIR CONDITIONING

A sophisticated biomimetic ingredient designed to function as a 'liquid cuticle' by replicating the protective 18-MEA lipid layer of the skin. This specialized keratin complex selectively targets damaged areas to restore the skin's natural shielding capacity and moisture retention.

Skin conditioning Barrier repair Surface smoothing Moisture retention

Science

This ingredient utilizes a cationic (positively charged) quaternary ammonium group to intelligently seek out and bind to negatively charged damaged sites on the skin and hair. By mimicking the structure of 18-Methyleicosanoic acid (18-MEA)—the primary lipid found in the skin's surface F-layer—it forms a seamless, protective film that reinforces barrier function and provides a smooth, conditioned texture.


Research

High confidence
Effective range 1–5%
Optimal

3%

Key findings

  1. 01 Manufacturer testing (Seiwa Kasei) validates its efficacy in mimicking the 18-MEA lipid layer to repair damaged surfaces when used between 1-5%.
  2. 02 Safety and compatibility studies cited by the CIR (2016) demonstrated that a 3% concentration in topical applications significantly supports skin barrier integrity without causing adverse reactions.

Transparency

Commonly dusted
Min. effective
1%
Red flag below
0.5%

Because it is a specialized complex, it is often included at 'claim' levels below 0.5% in mass-market products. At Moumoujus, we look for concentrations of at least 1-3% to ensure the biomimetic film-forming properties are physiologically active.


The Formula

Solubility
Water
Optimal pH 4 – 6
0 7 14

Stability

Highly stable in both oil-in-water and water-in-oil emulsions within an acidic to neutral pH range. It is thermo-sensitive; formulation must occur below high temperature thresholds to prevent degradation of the protein structure.

Synergies

  • Ceramides
  • Glycerin
  • Fatty acids

Conflicts

  • High concentrations of anionic surfactants
  • Strong oxidizing agents

Safety

CIR Status
Hydrolyzed Keratin core component is CIR-cleared
Max tested
5%
Pregnancy
Safe
Sensitization risk Low

While the specific succinoyl complex is relatively new, its parent component, Hydrolyzed Keratin, is established as safe for leave-on use up to 5%.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Valuable

An exceptional biomimetic agent for precision barrier repair and texture refinement, particularly in targeted treatment products.


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