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CETEARAMIDOETHYL DIETHONIUM HYDROLYZED RICE PROTEIN.

Valuable

A high-performance biomimetic repair agent derived from rice protein, engineered to restore the protective lipid layer of the hair and skin. It specifically targets damaged areas to reinstate hydrophobic protection and smooth the surface texture.

barrier repair hair conditioning skin conditioning smoothing

Science

This ingredient functions as a structural analog to 18-Methyleicosanoic acid (18-MEA), the natural lipid that coats the hair cuticle. Its cationic (positively charged) nature allows it to selectively bind to damaged, anionic sites on the hair and skin, effectively 'patching' the barrier and restoring water repellency through the reconstruction of the F-layer.


Research

High confidence
Effective range 0.3–5%
Optimal

1%

Key findings

  1. 01 Clinical evaluation at 0.6% demonstrated the successful restoration of the hydrophobic F-layer and structural repair of the cuticle.
  2. 02 Testing at 0.3% showed a significant reduction in surface friction, improving smoothness on severely bleached hair fibers.
  3. 03 Concentrations between 1.0% and 5.0% are clinically validated to accelerate drying time and enhance surface structural integrity.

Transparency

Commonly dusted
Min. effective
0.3%
Red flag below
0.1%

Because it is effective at very low concentrations (starting at 0.3%), many formulations include it at 'claim' levels below 0.1% for marketing purposes without achieving the functional barrier restoration shown in clinical data.


The Formula

Solubility
Water
Optimal pH 4 – 7
0 7 14

Stability

The ingredient is heat-stable and remains effective across standard cosmetic pH ranges. It is typically supplied in a preservative-free water/glycerin base.

Synergies

  • Glycerin
  • Non-ionic conditioners
  • Amphoteric surfactants

Conflicts

  • Anionic surfactants
  • Anionic polymers
  • Strongly anionic thickeners

Safety

CIR Status
Safe as used
Max tested
5%
Pregnancy
Safe
Sensitization risk Low

While the specific complex is not a standalone CIR entry, its components—hydrolyzed rice protein and glycerin—are well-documented as safe for topical application.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Valuable

An exceptionally precise biomimetic ingredient for restoring the lipid barrier in damaged hair and compromised skin profiles.


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