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Cereus Grandiflorus (Cactus) Extract.

Valuable CAS 8007-78-1 / ANTIOXIDANT, ASTRINGENT, HAIR CONDITIONING, SKIN CONDITIONING

Commonly known as the Queen of the Night, this botanical powerhouse thrives in extreme conditions, offering the skin a unique blend of hydration and structural renewal. It serves as a multifunctional bioactive that bridges the gap between surface conditioning and cellular revitalization.

Antioxidant Humectant Skin Conditioning Texture Refiner Anti-inflammatory

Science

The extract utilizes a rich profile of betalains and flavonoids to neutralize oxidative stress, while its high polysaccharide content acts as a humectant to lock in moisture. On a cellular level, it stimulates mitochondrial activity and keratinocyte migration, facilitating a mild enzymatic-like exfoliating effect that refines skin texture without the irritation typical of synthetic acids.


Research

High confidence
Effective range 1–5%
Optimal

3%

Key findings

  1. 01 Demonstrated broad-spectrum antioxidant protection and a reduction in IL-6 inflammatory markers in keratinocytes.
  2. 02 Clinical evaluation showed a significant reduction in stratum corneum cohesion, mimicking the exfoliating benefits of glycolic acid.
  3. 03 Evidence of increased mitochondrial activity in fibroblasts, suggesting improved cellular energy and repair.

Transparency

Commonly dusted
Min. effective
1%
Red flag below
0.1%

Due to its exotic botanical appeal, it is often included at concentrations below 0.1% for marketing purposes. To achieve the documented mitochondrial and exfoliating benefits, it must be formulated at 1% or higher.


The Formula

Solubility
Water
Optimal pH 6 – 7
0 7 14

Stability

Highly pH-sensitive; the extract loses efficacy and stability in acidic environments below pH 5.0. It requires a near-neutral formulation to maintain its bioactive integrity.

Synergies

  • Glycerin
  • Hyaluronic Acid
  • Niacinamide

Conflicts

  • Low pH L-Ascorbic Acid
  • Alpha Hydroxy Acids
  • Strong oxidizing agents

Safety

CIR Status
Safe as used
Max tested
5%
Pregnancy
Safe
Sensitization risk Low

Reviewed by the CIR in 2023 and found to be non-sensitizing. Safe for long-term topical use within the 1-5% range.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Valuable

A sophisticated botanical active that offers the rare combination of mitochondrial stimulation and gentle exfoliation, provided it is formulated at a neutral pH.


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References