Science
Mechanism of Action
As a lipophilic molecule, it inserts itself into the lipid bilayers of the skin's outermost layer. By mimicking the natural composition of the skin, it seals gaps in the intercellular matrix, significantly reducing transepidermal water loss (TEWL) and defending against external irritants.
Research
Clinical Evidence
High confidence0.2%
Key findings
- 01 Technical evaluations of the RepairLipid-S complex indicate that concentrations between 0.1% and 1.0% effectively penetrate the hair shaft to replenish lost lipids and restore gloss.
- 02 Safety and efficacy assessments by the CIR found that a 0.2% concentration is highly effective for maintaining the skin barrier in leave-on facial preparations.
Transparency
Dusting Analysis
Because ceramides are potent at low concentrations, they are rarely 'dusted' in the traditional sense; however, levels below 0.1% may be insufficient for meaningful barrier restoration and are often included primarily for marketing claims.
The Formula
Formulation
Stability
Heat-sensitive; should be incorporated during the cool-down phase of formulation to prevent degradation. It is highly stable in anhydrous systems and oil-in-water emulsions.
Synergies
- Cholesterol
- Fatty Acids
- Vitamin C (L-Ascorbic Acid)
- Liposomal delivery systems
Conflicts
- High processing temperatures
- Strong oxidizing agents
Safety
Safety Profile
Classified as a skin-identical lipid with an excellent safety profile for all life stages.
Your Skin
Skin Compatibility
Our Assessment
Verdict
An essential bio-mimetic lipid that provides targeted barrier support and improves moisture retention across all skin types.
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References
Sources