Science
Mechanism of Action
This ingredient stimulates fibroblast proliferation, leading to an increased synthesis of collagen and intracellular fibronectin. This action enhances the tensile strength of newly formed skin, thereby supporting firmness and elasticity, while also inhibiting the inflammatory phase linked to hypertrophic scars and keloids. Rich in triterpenoids, flavonoids, and phenolic acids, it delivers powerful antioxidant properties by neutralizing free radicals, which mitigates oxidative stress and may visibly reduce signs of aging like fine lines and wrinkles. It also fortifies the skin's protective barrier, aids in the restoration of damaged skin cells, and provides defense against environmental stressors such as pollution and UV radiation, resulting in softer, smoother, and more hydrated skin.
Research
Clinical Evidence
Low confidenceN/A
Transparency
Dusting Analysis
The Formula
Formulation
Stability
While an optimal pH range for cosmetic formulations is not specified, in vitro studies indicate an optimal pH of 5.7±0.1 for Centella Asiatica callus culture growth. Browning of callus in culture can occur due to the accumulation and oxidation of phenolic compounds, suggesting potential stability considerations in cosmetic formulations.
Safety
Safety Profile
The Cosmetic Ingredient Review (CIR) Expert Panel concluded that Centella Asiatica Callus Culture is safe for use in cosmetics when formulated to be non-sensitizing. Specific data regarding its safety during pregnancy and breastfeeding are currently insufficient, therefore consultation with a healthcare professional is advised for individuals in these categories.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Centella Asiatica Callus Culture is a valuable multi-benefit ingredient, offering significant support for collagen production, barrier integrity, antioxidant defense, and soothing properties, making it suitable for enhancing the health and appearance of all skin types.
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References
Sources