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CEDRENE.

Questionable CAS 11028-42-5 / PERFUMING

Cedrene is a naturally occurring terpene derived from cedarwood, recognized for its potential mild antimicrobial and anti-inflammatory properties. While commonly used in fragrance applications, its integration into precision skincare formulations necessitates careful consideration due to potential dermal sensitization.

Anti-inflammatory Antimicrobial Fragrance

Science

Cedrene is hypothesized to exert its effects by modulating inflammatory pathways and demonstrating mild antimicrobial activity, thereby contributing to potential skin calming and purifying benefits.


Research

Low confidence
Effective range N/A
Optimal

N/A


Transparency

Not commonly dusted

The Formula

Solubility
Oil
Optimal pH N/A
0 7 14

Stability

As a terpene, Cedrene is prone to oxidation upon exposure to air, which can lead to polymerization. It exhibits stability under typical storage conditions.


Safety

CIR Status
Not reviewed
Max tested
0.38%
Sensitization risk High

Cedrene is a restricted ingredient by the International Fragrance Association (IFRA) due to documented concerns regarding dermal sensitization. While some reports indicate no irritation or sensitization at a 5% concentration in human experience, other sources highlight its potential to cause sensitization via skin contact and general irritation to the skin and eyes. The maximum concentration for leave-on products like face moisturizers is 0.38% according to IFRA standards.


Your Skin

No Normal
No Dry
No Oily
No Sensitive
Irritancy High
Comedogenicity Unknown

Our Assessment

Questionable

Cedrene presents potential mild antimicrobial and anti-inflammatory benefits, but its high risk of dermal sensitization and IFRA restrictions make its suitability for precision skincare formulations questionable.


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