Science
Mechanism of Action
This extract functions by combating oxidative stress and promoting dermal repair. It actively reduces levels of metalloproteinase-1 (MMP-1), an enzyme that degrades collagen, and decreases protein carbonyls, markers of oxidative damage. Simultaneously, it stimulates the production of vital skin components such as collagen and hyaluronic acid. Furthermore, it modulates the skin's inflammatory response by protecting against UV-induced increases in pro-inflammatory cytokines, specifically IL-1β and IL-6.
Research
Clinical Evidence
Medium confidenceN/A
Key findings
- 01 Increased cell viability in human fibroblasts and keratinocytes exposed to UV radiation at concentrations exceeding 20 μg/mL.
- 02 A concentration of 1000 μg/mL significantly boosted protein content (cell number) by 7.5-fold and cell viability by 1.4-fold in UV-exposed human fibroblasts and keratinocytes.
- 03 Decreased metalloproteinase-1 and protein carbonyl levels, increased collagen and hyaluronic acid contents, and protected against UV-induced increase in pro-inflammatory cytokines IL-1β and IL-6 in human fibroblasts and keratinocytes exposed to UV radiation.
Transparency
Dusting Analysis
The Formula
Formulation
Safety
Safety Profile
The Cosmetic Ingredient Review (CIR) has not thoroughly assessed Cecropia Obtusa Bark Extract, leading to an 'insufficient data' status. Other reputable sources like Paula's Choice categorize it as 'not rated' with 'no known benefits' listed in their unrated section, despite scientific literature indicating otherwise. Toxicity data, including oral, parenteral, dermal, and inhalation toxicity, remains undetermined for this ingredient.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Cecropia Obtusa Bark Extract shows promising in vitro efficacy for photo-protection, anti-aging, and anti-inflammatory benefits, though further comprehensive safety and in vivo human data are needed for full characterization.
Related
Similar Ingredients
Finding similar ingredients…