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CASTANOPSIS CUSPIDATA STEM EXTRACT.

Valuable CAS - / ANTIMICROBIAL, ANTIOXIDANT, ASTRINGENT, SKIN CONDITIONING - EMOLLIENT

A potent botanical bioactive derived from the Japanese Chinquapin tree, utilized for its dual-action approach to structural aging and pigment regulation. This extract is characterized by a high concentration of polyphenolic compounds that provide robust defense against environmental stressors.

antioxidant brightening collagen-support antimicrobial skin conditioning astringent

Science

The extract functions as a high-performance antioxidant via epicatechin and procyanidin B2, which neutralize reactive oxygen species (ROS). It further improves skin architecture by stimulating collagen production in fibroblasts and inhibits the tyrosinase enzyme to modulate melanin synthesis for a brighter, more even complexion.


Research

Medium confidence
Effective range 0.31–50%
Optimal

2.5%

Key findings

  1. 01 In vitro evaluation (US Patent 20140154195A1) demonstrates significant tyrosinase inhibition and collagen fibroblast stimulation at concentrations between 0.31% and 2.5%.

Transparency

Commonly dusted
Min. effective
0.31%
Red flag below
0.1%

While this extract is often listed at very low concentrations for label claims, molecular efficacy for collagen support and brightening begins at 0.31%. Formulations utilizing less than this amount may only provide basic antioxidant protection.


The Formula

Solubility
Water
Optimal pH 4 – 7
0 7 14

Stability

Highly stable in aqueous and water-glycol systems. Due to the natural polyphenol content, formulations may undergo slight color shifts if exposed to UV light or temperatures exceeding 40°C for extended periods.

Synergies

  • Ascorbic Acid
  • Niacinamide
  • Peptides

Conflicts

  • strong oxidizing agents
  • high pH environments (>8.0)

Safety

CIR Status
Not reviewed
Max tested
50%
Pregnancy
Safe
Sensitization risk Low

While the 2010 CIR notice indicated insufficient data, its long-term widespread use in the East Asian cosmetic market and low irritancy profile suggest a high safety margin at typical formulation levels.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Valuable

A versatile and gentle botanical active that effectively targets both oxidative damage and loss of elasticity when formulated at precise concentrations.


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