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CASSIA ANGUSTIFOLIA SEED POLYSACCHARIDE.

Valuable CAS 85187-05-9 / SKIN CONDITIONING

A refined botanical polysaccharide derived from the Senna plant, serving as a high-performance plant-based alternative to hyaluronic acid. It creates a breathable, moisture-binding film on the epidermis while biologically addressing the visible signs of skin fatigue.

Humectant Film-forming agent Skin conditioning Anti-stress active

Science

This ingredient functions through a dual-action moisture strategy: it establishes a hydro-filmic barrier to lock in surface hydration while simultaneously rebalancing cortisol receptors in keratinocytes. By mitigating stress-induced aging, it stimulates fibroblasts to increase the natural production of endogenous hyaluronic acid and collagen.


Research

High confidence
Effective range 2.5–5%
Optimal

5%

Key findings

  1. 01 Clinical evaluation at 5% concentration demonstrated a 44% improvement in immediate hydration, significantly outperforming synthetic sodium hyaluronate in moisture retention after 24 hours.
  2. 02 Ex vivo studies revealed a 99% increase in endogenous hyaluronic acid synthesis and a 61% reduction in cortisol-generating enzymes at concentrations between 2.5% and 5%.
  3. 03 Research indicates a 215% increase in cortisol repressors and a 13% boost in collagen synthesis, contributing to improved skin radiance and smoothness.

Transparency

Commonly dusted
Min. effective
2.5%
Red flag below
1%

Many formulations include this ingredient at sub-clinical levels (<1%) for its 'botanical hyaluronic acid' marketing claim. However, the quantified anti-stress and collagen-boosting benefits require a minimum concentration of 2.5% to 5%.


The Formula

Solubility
Water
Optimal pH 4 – 8
0 7 14

Stability

Highly stable in water-based systems and maintains its viscosity even under significant temperature fluctuations. Its high molecular weight provides excellent film-forming properties.

Synergies

  • Glycerin
  • Niacinamide
  • Panthenol
  • Peptides

Conflicts

  • High electrolyte or salt concentrations (may thin the formula)
  • High alcohol content (can cause precipitation)
  • Cationic surfactants

Safety

CIR Status
Safe as used
Max tested
5%
Pregnancy
Safe
Sensitization risk Low

Reviewed and confirmed safe by the CIR Expert Panel (2015) within the polysaccharide gums group and registered with the FDA VCRP.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Valuable

An exceptional botanical active that provides superior hydration to hyaluronic acid while uniquely protecting the skin from cortisol-induced structural degradation.


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References