Science
Mechanism of Action
This extract utilizes a high concentration of luteolin and tricin to suppress inflammatory signaling molecules, specifically IL-1β, IL-6, and TNF-α. It simultaneously inhibits lipoxygenase to modulate lipid synthesis and MMP-1 to prevent collagen degradation, while its polysaccharide content provides radical scavenging to neutralize oxidative stress.
Research
Clinical Evidence
Medium confidence1.5%
Key findings
- 01 Demonstrated a Minimum Inhibitory Concentration (MIC) of 62.5 µg/mL (0.00625%) against Candida albicans, establishing its role as a botanical antimicrobial.
- 02 Identified as a potent antioxidant with an IC50 of 0.03 mg/mL for ABTS radical scavenging.
- 03 Patented data confirms efficacy between 0.1% and 5% for the inhibition of lipoxygenase (sebum control) and MMP-1 (anti-aging).
Transparency
Dusting Analysis
While this ingredient shows antioxidant activity at extremely low levels (0.003%), its primary structural benefits for sebum regulation and anti-aging are achieved at 0.1% or higher. Concentrations below this threshold in 'active' serums may indicate label claim usage.
The Formula
Formulation
Stability
Heat-sensitive due to volatile oils and flavonoids; must be incorporated during the cool-down phase at temperatures below 40°C.
Synergies
- Niacinamide (enhanced sebum control)
- Hyaluronic Acid (polysaccharide-driven hydration)
- Centella Asiatica (amplified soothing effects)
Conflicts
- Strong oxidizing agents
- High-temperature processing
Safety
Safety Profile
Listed in the IECIC for use in China. Historically used in botanical medicine with no reported irritancy, though comprehensive CIR safety dossiers are pending.
Your Skin
Skin Compatibility
Our Assessment
Verdict
A versatile botanical powerhouse that delivers measurable antimicrobial and anti-inflammatory benefits, particularly effective for blemish-prone and aging skin.
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