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CAREX MEYERIANA LEAF/STEM EXTRACT.

Valuable CAS - / SKIN CONDITIONING

Derived from Wula Sedge, this multifunctional botanical extract is rich in specialized flavonoids and polysaccharides that provide a defensive shield for the skin. It is primarily utilized in precision formulations to balance sebum production while offering potent antioxidant and antimicrobial support.

Skin Conditioning Antioxidant Soothing Sebum Regulator Antimicrobial

Science

This extract utilizes a high concentration of luteolin and tricin to suppress inflammatory signaling molecules, specifically IL-1β, IL-6, and TNF-α. It simultaneously inhibits lipoxygenase to modulate lipid synthesis and MMP-1 to prevent collagen degradation, while its polysaccharide content provides radical scavenging to neutralize oxidative stress.


Research

Medium confidence
Effective range 0.003–5%
Optimal

1.5%

Key findings

  1. 01 Demonstrated a Minimum Inhibitory Concentration (MIC) of 62.5 µg/mL (0.00625%) against Candida albicans, establishing its role as a botanical antimicrobial.
  2. 02 Identified as a potent antioxidant with an IC50 of 0.03 mg/mL for ABTS radical scavenging.
  3. 03 Patented data confirms efficacy between 0.1% and 5% for the inhibition of lipoxygenase (sebum control) and MMP-1 (anti-aging).

Transparency

Not commonly dusted
Min. effective
0.1%
Red flag below
0.05%

While this ingredient shows antioxidant activity at extremely low levels (0.003%), its primary structural benefits for sebum regulation and anti-aging are achieved at 0.1% or higher. Concentrations below this threshold in 'active' serums may indicate label claim usage.


The Formula

Solubility
Both
Optimal pH 4.5 – 7
0 7 14

Stability

Heat-sensitive due to volatile oils and flavonoids; must be incorporated during the cool-down phase at temperatures below 40°C.

Synergies

  • Niacinamide (enhanced sebum control)
  • Hyaluronic Acid (polysaccharide-driven hydration)
  • Centella Asiatica (amplified soothing effects)

Conflicts

  • Strong oxidizing agents
  • High-temperature processing

Safety

CIR Status
Not reviewed
Sensitization risk Low

Listed in the IECIC for use in China. Historically used in botanical medicine with no reported irritancy, though comprehensive CIR safety dossiers are pending.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Valuable

A versatile botanical powerhouse that delivers measurable antimicrobial and anti-inflammatory benefits, particularly effective for blemish-prone and aging skin.


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