Get a Free 5ml Mini Now Free 5ml Mini With Every Order of The Mantle

CARBOXYMETHYL CELLULOSE ACETATE BUTYRATE.

Valuable / EMULSION STABILISING, FILM FORMING, VISCOSITY CONTROLLING

A high-performance amphiphilic cellulose derivative designed to stabilize complex active ingredients and optimize their delivery into the skin. It creates a sophisticated, breathable film that mimics the surface energy of natural collagen, ensuring both biocompatibility and sustained performance.

Controlled-release agent Film former Rheology modifier Active stabilizer Viscosity controller

Science

This ingredient functions as a structural architect for skincare formulas. By maintaining a high glass transition temperature, it prevents the crystallization of potent actives like antioxidants, keeping them in a more bioavailable amorphous state. Its unique film-forming properties establish a controlled-release matrix that ensures a steady, zero-order delivery of ingredients over a 24-hour period while simultaneously refining product texture.


Research

High confidence
Effective range 10–25%
Optimal

15%

Key findings

  1. 01 Demonstrated ability to increase the solubility of poorly soluble actives such as Quercetin and Curcumin by over 300% through the formation of amorphous solid dispersions.
  2. 02 Clinical evaluation confirms non-irritating and non-sensitizing profile even at maximum concentrations up to 100%.

Transparency

Not commonly dusted
Min. effective
5%
Red flag below
1%

In precision skincare, this is a functional powerhouse rather than a 'marketing' active. While it is safe at high levels, its primary value lies in stabilizing other ingredients; concentrations below 5% may indicate it is used purely for texture rather than for its advanced controlled-release capabilities.


The Formula

Solubility
Both
Optimal pH 4.5 – 7.5
0 7 14

Stability

Requires partial neutralization (often with amines) to achieve water-dispersibility. It is highly resistant to heat and hydrolysis, making it an exceptional stabilizer for long-shelf-life products.

Synergies

  • Quercetin
  • Curcumin
  • Hydrophobic antioxidants
  • UV Filters

Conflicts

  • Strongly acidic environments (below pH 4.0)
  • Excessive neutralization

Safety

CIR Status
Safe as used
Max tested
100%
Pregnancy
Safe
Sensitization risk Low

Classified as non-toxic and non-photosensitizing. Its long history as a pharmaceutical excipient reinforces its safety profile for topical use.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Valuable

An indispensable technical ingredient for stabilizing unstable actives and ensuring precision 24-hour ingredient delivery.


Related

Finding similar ingredients…