Get a Free 5ml Mini Now Free 5ml Mini With Every Order of The Mantle

CARBONIC ACID.

Valuable CAS 463-79-6 / NOT REPORTED

A dynamic skin-oxygenating agent formed when carbon dioxide dissolves in water, primarily utilized in carboxytherapy-inspired treatments. It serves as a physiological catalyst that revitalizes cellular metabolism and enhances the skin's natural barrier through controlled pH modulation.

Microcirculation stimulant Barrier repair Buffering agent Metabolic activator

Science

It functions via the 'Bohr Effect': as carbonic acid lowers the localized pH of the skin, it signals hemoglobin to release oxygen directly into the tissues. This process induces rapid vasodilation and boosts microcirculation, providing a surge of metabolic energy to skin cells while simultaneously stimulating ceramide production to reinforce the lipid barrier.


Research

Medium confidence
Effective range 350–1500%
Optimal

N/A

Key findings

  1. 01 A 4-week study involving thrice-weekly applications showed a 27% increase in skin radiance and a 19% improvement in microcirculation.
  2. 02 Research indicates that concentrations between 350-1500 mg/L of dissolved CO2 effectively stimulate epidermal ceramide synthesis and reduce transepidermal water loss (TEWL).

Transparency

Commonly dusted
Min. effective
350%

Often marketed in 'bubble masks' at negligible concentrations for sensory effect only. True efficacy requires specific delivery systems to maintain the 350-1500 mg/L threshold needed to trigger the Bohr Effect.


The Formula

Solubility
Water
Optimal pH 5 – 7
0 7 14

Stability

Highly volatile and prone to rapid degassing. Effective delivery requires pressurized canisters or in-situ generation via dual-chamber carboxy systems to prevent the acid from decomposing back into CO2 gas.

Synergies

  • Ceramides
  • Hyaluronic Acid
  • Vasodilators

Conflicts

  • High pH environments
  • High temperatures
  • Open-air packaging

Safety

CIR Status
Not reviewed (salts rated safe)
Pregnancy
Safe
Sensitization risk Low

As a natural physiological constituent, it is exceptionally well-tolerated. Safety profiles for its carbonate and bicarbonate salts suggest it is non-toxic for topical application.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Valuable

An innovative physiological tool for boosting radiance and barrier health, provided it is stabilized through advanced delivery systems.


Related

Finding similar ingredients…