Get a Free 5ml Mini Now Free 5ml Mini With Every Order of The Mantle
Moumoujus

CARBON DIOXIDE.

Valuable CAS 124-38-9 / PROPELLANT

A gaseous active frequently utilized in carboxytherapy to stimulate cutaneous respiration and revitalize dull complexions. By leveraging physiological gas exchange, it serves as a powerful catalyst for internal skin oxygenation and enhanced microcirculation.

Summary

oxygenating agent vasodilator propellant metabolic stimulant

Science

Mechanism of Action

Carbon Dioxide operates through the 'Bohr Effect.' When introduced to the skin, it increases local CO2 concentrations, signaling hemoglobin to release bound oxygen into the tissues. This surge in bioavailable oxygen triggers vasodilation, accelerates cellular metabolism, and encourages the synthesis of structural proteins like collagen.

Research

Clinical Evidence

High confidence
Effective range ≥60%
Optimal

N/A

Key findings

  1. 01 Concentrations ≥60 mg/L were found to actively promote dermal blood flow and preserve the skin's barrier function against harsh winter conditions.
  2. 02 Ten weeks of consistent CO2 exposure resulted in a 16% increase in skin firmness and a 12% improvement in global aesthetic appearance.
  3. 03 CO2 treatments significantly elevated transcutaneous oxygen tension (tcPO2) levels compared to mechanical exfoliation methods.

Transparency

Dusting Analysis

Commonly dusted
Min. effective
60%
Red flag below
10%

In many 'carbonated' products, CO2 is present at negligible levels merely for sensory 'fizz' or as a propellant. To achieve the Bohr Effect and genuine physiological benefits, it must be maintained at a concentration of at least 60 mg/L or generated via high-dose in-situ reactions.

The Formula

Formulation

Solubility
Water
Optimal pH 4 – 5.5
0 7 14

Stability

Highly volatile at atmospheric pressure; it requires pressurized delivery systems or dual-phase 'in-situ' activation (mixing an acid and a carbonate) to remain effective before dissipating.

Synergies

  • Sodium Bicarbonate
  • Organic Acids (Citric/Malic)
  • Vascular stimulants

Conflicts

  • Alkaline environments (pH > 7.0)
  • Carbomer-based thickeners
  • Non-pressurized, open-air packaging

Safety

Safety Profile

CIR Status
Not reviewed
Max tested
100%
Pregnancy
Safe
Sensitization risk Low

Recognized as FDA GRAS (Generally Recognized As Safe). While not formally reviewed as an active by the CIR, it is a standard, safe propellant and food-grade gas.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Verdict

Valuable

A sophisticated physiological tool that optimizes skin oxygenation from the inside out, provided it is formulated in stable, high-concentration delivery systems.

Related

Similar Ingredients

Finding similar ingredients…

References

Sources