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CAPRYLYL PYRROLIDONE.

Valuable CAS 2687-94-7 / CLEANSING, FOAMING, HAIR CONDITIONING, SURFACTANT - CLEANSING

A high-performance nonionic surfactant and specialized penetration enhancer designed to maximize the bioavailability of active ingredients. It is frequently utilized in technical formulations to stabilize complex molecules and ensure the uniform distribution of UV filters and antioxidants.

Penetration Enhancer Solubilizer Surfactant Stabilizer Viscosity Controller

Science

This ingredient functions by temporarily reorganizing the ordered intercellular lipid bilayers of the stratum corneum. By reducing the skin barrier's resistance, it increases the thermodynamic activity of accompanying molecules, allowing active ingredients like L-ascorbic acid to partition more efficiently into the deeper epidermal layers.


Research

High confidence
Effective range 0.027–5%
Optimal

2%

Key findings

  1. 01 Demonstrated significant enhancement of transdermal penetration for L-ascorbic acid concentrations up to 40% in dermatological compositions.
  2. 02 Proven effective at low concentrations (0.027-0.057%) for preventing the crystallization of organic UV filters like Tinosorb S, ensuring formula homogeneity.

Transparency

Not commonly dusted
Min. effective
0.5%
Red flag below
0.01%

While used at very low levels (under 0.1%) as a stabilizer for UV filters, its primary functional role as a penetration enhancer typically requires concentrations between 0.5% and 2.0%.


The Formula

Solubility
Both
Optimal pH 4 – 12
0 7 14

Stability

Exhibits exceptional stability across a broad pH spectrum and is highly salt-tolerant. It maintains structural integrity even in complex polymer systems.

Synergies

  • L-Ascorbic Acid
  • Tinosorb S
  • Sodium Dodecyl Sulfate

Conflicts

  • Strong bases
  • Strong oxidizing agents

Safety

CIR Status
Not reviewed
Max tested
5%
Sensitization risk Moderate

Classified as corrosive in its 100% pure form; however, it is considered safe for topical use when diluted below 5%. It should not be used in products that are aerosolized (sprays).


Your Skin

Yes Normal
No Dry
Yes Oily
No Sensitive
Irritancy Moderate
Comedogenicity Low

Our Assessment

Valuable

An essential auxiliary for high-precision formulations requiring deep delivery of actives, though its barrier-disrupting nature makes it less suitable for sensitive skin types.


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References