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Capryloyl Silk Amino Acids.

Valuable CAS 227200-38-6 / CLEANSING, HAIR CONDITIONING, SURFACTANT - CLEANSING

A sophisticated lipo-amino acid that merges the lipid-balancing properties of caprylic acid with the structural proteins of silk. This amphiphilic molecule serves as a dual-action agent, providing exceptionally gentle cleansing while reinforcing the skin's moisture barrier.

Skin Conditioning Surfactant Humectant Sebum Regulator

Science

By combining a lipophilic capryloyl chain with hydrophilic silk amino acids, this ingredient acts as a biomimetic conditioner. The fatty acid component helps regulate surface sebum and provides mild antimicrobial support, while the silk amino acids create a breathable, film-forming shield that preserves hydration and enhances cutaneous elasticity.


Research

High confidence
Effective range 1–10%
Optimal

6%

Key findings

  1. 01 Safety assessments on structurally analogous amino acid alkyl amides confirmed the compound as a non-irritant and non-sensitizer in human clinical trials.
  2. 02 Related lipo-amino acids demonstrated a total absence of dermal irritation or sensitization in human subjects, reinforcing the high tolerance profile of this chemical class.

Transparency

Not commonly dusted
Min. effective
1%
Red flag below
0.5%

While often used at lower levels for marketing 'silk' claims, it requires concentrations above 1% to function effectively as a primary conditioning agent or surfactant.


The Formula

Solubility
Water
Optimal pH 5 – 7
0 7 14

Stability

Exhibits excellent stability in aqueous systems and emulsions; should be integrated into the water phase.

Synergies

  • Hyaluronic Acid
  • Glycerin
  • Mild Non-ionic Surfactants

Conflicts

  • Strong oxidizing agents
  • High-molecular-weight cationic polymers

Safety

CIR Status
Safe as used
Max tested
10%
Pregnancy
Safe
Sensitization risk Low

The CIR Expert Panel considers this ingredient safe for cosmetic use when formulated to maintain the skin's natural pH balance.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Valuable

An exceptional multi-functional ingredient that bridges the gap between effective sebum control and luxurious skin conditioning.


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