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CAPRYLOYL SERINE/SILK AMINO ACID METHYL ESTERS.

Valuable / HAIR CONDITIONING, SKIN CONDITIONING

A sophisticated lipoamino acid derivative that bridges the gap between antimicrobial protection and structural skin conditioning. By fusing caprylic acid with silk protein components, it delivers a dual-action approach to purifying the skin microbiome while reinforcing the moisture barrier.

antibacterial sebum regulation skin conditioning antifungal mattifying agent

Science

This ingredient operates through a bipartite mechanism: its capryloyl lipid chain disrupts the cellular membranes of acne-causing bacteria (C. acnes) and fungal pathogens (Malassezia), while its silk amino acid core acts as a humectant to bind moisture. Additionally, it aids in regulating follicular sebum flow and provides a tactile 'soft focus' finish to the skin surface.


Research

High confidence
Effective range 1–2%
Optimal

2%

Key findings

  1. 01 Clinical evaluations conducted by Laboratoires ASEPTA demonstrate significant inhibition of S. aureus and C. acnes at concentrations between 1% and 2%.
  2. 02 Dermatological assessments of patented 2% formulations confirm a measurable reduction in surface sebum and enhanced skin suppleness.

Transparency

Commonly dusted
Min. effective
1%
Red flag below
0.1%

Because it is a patented specialty ester often marketed for its premium silk origins, it is frequently used at 'claim' levels (below 0.1%) in mass-market products. To achieve true microbiome-balancing and sebum-regulating benefits, it must be formulated at 1% or higher.


The Formula

Solubility
Oil
Optimal pH 5 – 7
0 7 14

Stability

Highly stable in standard conditions but vulnerable to ester hydrolysis if exposed to highly acidic (pH <4) or alkaline (pH >8) environments.

Synergies

  • Salicylic Acid
  • Niacinamide
  • Glycerin

Conflicts

  • Strong oxidizing agents
  • Extreme pH adjusters

Safety

CIR Status
Not reviewed
Max tested
2%
Pregnancy
Safe
Sensitization risk Low

While a specific CIR report is pending, its constituent parts—Caprylic Acid and Silk Amino Acids—have extensive safety profiles in cosmetic use.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Valuable

An exceptional multi-tasking active for blemish-prone yet dehydrated skin, providing targeted antimicrobial action without compromising the skin barrier.


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