Science
Mechanism of Action
This peptide functions as a targeted autophagy activator for sebocytes, essentially triggering the skin's cellular 'recycling' process to modulate sebum formation. By inhibiting inflammatory cytokines triggered by C. acnes, it prevents the cascade of irritation that leads to visible blemishes and helps restore a balanced hydrolipidic film.
Research
Clinical Evidence
High confidence2%
Key findings
- 01 Clinical evaluations demonstrated a 30% reduction in active acne lesions and inflammatory pimples over an 8-week trial period.
- 02 Usage at 2% concentration significantly reduced surface oiliness and normalized sebaceous gland activity without causing the dryness typical of traditional anti-acne agents.
Transparency
Dusting Analysis
As a high-performance specialty peptide (often marketed under the name Sebodulin™), it is frequently included at 'label claim' amounts below 1% to save costs. At Moumoujus, we consider levels below 1% insufficient to trigger the autophagy signaling required for visible sebum regulation.
The Formula
Formulation
Stability
Highly stable in aqueous solutions; however, we recommend cold processing during the final formulation stage to preserve the delicate peptide structure.
Synergies
- Niacinamide
- Salicylic Acid
- Zinc PCA
Conflicts
- Proteolytic enzymes
- Strong oxidizing agents
- pH levels below 3.5 or above 8.0
Safety
Safety Profile
Manufacturer-led RIPT testing confirms the ingredient is non-irritating and well-tolerated by sensitive skin types.
Your Skin
Skin Compatibility
Our Assessment
Verdict
A sophisticated, non-drying alternative to traditional oil-control ingredients that works with the skin's biological processes to reduce lesions and shine.
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References
Sources