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CAPRYLETH-4 CARBOXYLIC ACID.

Valuable CAS 53563-70-5 / CLEANSING, SURFACTANT - CLEANSING, SURFACTANT - EMULSIFYING

An advanced anionic surfactant that bridges the gap between high-performance cleansing and biocompatibility. Its unique ether-carboxylic structure allows it to effectively lift impurities while preserving the delicate lipid architecture of the skin barrier.

Surfactant Cleansing Agent Emulsifying Agent Penetration Enhancer

Science

It functions as a mild surfactant by reducing the surface tension of water, allowing for the emulsification of oils and debris. Unlike traditional surfactants that can penetrate too deeply and cause irritation, its large polar head group restricts action to the surface, while its ethoxylated chain temporarily reorganizes lipid bilayers to improve the absorption of lipophilic active ingredients.


Research

High confidence
Effective range 0.5–5%
Optimal

2.5%

Key findings

  1. 01 Demonstrated superior skin barrier maintenance compared to traditional sulfates (SLS/SLES) while achieving equivalent cleansing power.
  2. 02 Proven to act as a percutaneous absorption enhancer for lipophilic molecules by optimizing stratum corneum permeability.

Transparency

Not commonly dusted
Min. effective
0.5%
Red flag below
0.1%

Typically utilized at functional levels between 0.5% and 5%. Concentrations below 0.1% are likely insufficient to provide meaningful surfactant or penetration-enhancing benefits.


The Formula

Solubility
Water
Optimal pH 5 – 9.5
0 7 14

Stability

Exhibits exceptional stability across a wide pH spectrum and remains effective in hard water, preventing the formation of insoluble mineral 'scum'.

Synergies

  • Lipophilic actives
  • Non-ionic surfactants
  • Emollients

Conflicts

  • Strong oxidizing agents
  • Highly cationic conditioning agents

Safety

CIR Status
Safe as used
Max tested
5%
Pregnancy
Safe
Sensitization risk Low

Safe for use up to 5% in rinse-off products; leave-on formulations are typically restricted to under 1% to ensure non-irritancy.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Valuable

A sophisticated, low-irritation surfactant that excels in sensitive skin formulations by providing efficient cleansing and enhanced active delivery without disrupting the barrier.


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