Science
Mechanism of Action
As a non-ionic surfactant, it lowers the surface tension of water to effectively emulsify debris and sebum for easy removal. It enhances formulation structural integrity by building micellar networks that increase viscosity and strengthens the interfacial film around air bubbles to ensure a dense, long-lasting foam.
Research
Clinical Evidence
High confidence2%
Key findings
- 01 At a concentration of 0.5%, Capramide DEA acts as a potent co-surfactant, accelerating the biocidal action of antimicrobial agents to achieve a >5 log reduction of common bacteria within 30 seconds.
- 02 Studies at 2.0% demonstrate its ability to stabilize formulations and maintain the integrity of active cleansing agents without compromising the formula's therapeutic benefits.
- 03 Safety data at 10.0% indicates minimal subjective and clinical irritation during prolonged human bathing trials.
Transparency
Dusting Analysis
Because Capramide DEA is a functional stabilizer rather than a primary active, it is rarely 'dusted' for marketing claims. However, levels below 0.5% may fail to provide significant rheological or foam-boosting benefits in professional-grade cleansers.
The Formula
Formulation
Stability
Maintains stability across a broad pH range (3.5–10), though concentrated solutions are naturally alkaline. It is thermally sensitive and should not be processed or stored at temperatures exceeding 89°F (31.7°C).
Synergies
- Chloroxylenol (PCMX)
- Anionic surfactants
- Antimicrobial agents
Conflicts
- N-nitrosating agents (Sodium Nitrite, Bronopol)
- Strong mineral acids
- Strong bases
Safety
Safety Profile
Safety is dependent on the absence of nitrosating agents to prevent the formation of nitrosamines. Strict adherence to EU standards (secondary amine content <0.5%) is required for finished product safety.
Your Skin
Skin Compatibility
Our Assessment
Verdict
An effective rheology modifier and lather enhancer that also provides significant synergistic support for antimicrobial cleansing systems.
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References
Sources