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CANNABISAMIDOPROPYL HYDROXYSULTAINE.

Valuable / SKIN CONDITIONING, SURFACTANT - CLEANSING, SURFACTANT - EMULSIFYING, SURFACTANT - FOAM BOOSTING, VISCOSITY CONTROLLING

A high-performance, hemp-derived amphoteric surfactant that provides exceptional mildness and conditioning properties in cleansing formulations. Unlike traditional coconut-based alternatives, it utilizes a long-chain C18 fatty acid profile to enhance skin feel while maintaining structural integrity in sulfate-free systems.

Surfactant Cleansing agent Foam booster Skin conditioning agent Viscosity controller

Science

As a zwitterionic surfactant, it carries both positive and negative charges, allowing it to organize into mixed micelles when paired with anionic cleansers. This molecular arrangement physically shields the skin from the aggressive protein denaturation typically caused by harsh surfactants, while its C18-dominant lipid chain provides superior emolliency and viscosity-building compared to shorter-chain sultaines.


Research

High confidence
Effective range 1–10%
Optimal

5%

Key findings

  1. 01 Zein solubility tests (2023) confirmed 0% increase in protein denaturation at 1% solids, demonstrating significantly lower irritation potential than standard surfactants.
  2. 02 Technical analysis shows superior viscosity-building and salt-response improvements in sulfate-free systems compared to C12-C14 sultaine counterparts.

Transparency

Not commonly dusted
Min. effective
1%
Red flag below
0.5%

As a functional surfactant and viscosity builder, it is typically used at levels above 1% to achieve the desired foam and texture; levels below this in a primary cleanser may indicate it is being used for 'label claim' regarding its hemp derivation.


The Formula

Solubility
Water
Optimal pH 5 – 8.5
0 7 14

Stability

Exhibits robust stability across a wide pH spectrum (2.0–12.0) and maintains integrity at processing temperatures up to 90°C.

Synergies

  • Anionic surfactants
  • Sulfate-free cleansing bases
  • Cationic conditioning agents

Conflicts

  • None reported

Safety

CIR Status
Safe as used
Pregnancy
Safe
Sensitization risk Low

Categorized under the broader CIR safety umbrella for amidopropyl betaines and sultaines; it is readily biodegradable and free of Prop 65 listed contaminants.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Valuable

An elite, low-irritation surfactant that bridges the gap between effective cleansing and skin-barrier protection through its unique hemp-based lipid profile.


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