Science
Mechanism of Action
This ingredient functions as a bioavailable emollient through transesterification, which attaches hydrophilic PEG-8 groups to the hemp oil's fatty acid chains. Once applied, it forms a lightweight, non-occlusive film that reinforces the stratum corneum's lipid barrier, effectively trapping moisture and reducing transepidermal water loss (TEWL) while delivering Omega-3 and Omega-6 nutrients.
Research
Clinical Evidence
High confidence3%
Key findings
- 01 In-vivo trials utilizing a 3.0% concentration demonstrated a measurable reduction in TEWL and significant restoration of skin barrier integrity.
- 02 A clinical study on scalp health involving a 1-5% complex showed a 20.6% increase in hair density and improved scalp condition, with high subject tolerance.
Transparency
Dusting Analysis
Because this ingredient also functions as a solubilizer and surfactant, it is often included at functional levels; however, concentrations below 1% may provide label appeal without the therapeutic lipid-replenishing benefits seen in clinical data.
The Formula
Formulation
Stability
Highly stable in water-based systems and oil-in-water emulsions. It is sensitive to hydrolysis if the pH drops below 3.0 or exceeds 10.0.
Synergies
- Humectants
- Other vegetable-derived esters
- Mild surfactants
Conflicts
- Strong oxidizing agents
- High electrolyte concentrations
- Strong acids and bases
Safety
Safety Profile
Classified as safe when formulated to be non-irritating; manufacturing must strictly monitor for 1,4-dioxane and ethylene oxide residuals.
Your Skin
Skin Compatibility
Our Assessment
Verdict
An excellent multi-functional ingredient for maintaining barrier health in water-based formulas without compromising texture or clogging pores.
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References
Sources