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CANNABIS SATIVA CALLUS CULTURE LYSATE EXTRACT.

Valuable / HAIR CONDITIONING, SKIN CONDITIONING

A pioneering neuro-cosmetic active derived from plant stem cells that bridges the gap between topical skincare and emotional well-being. By modulating the skin's microbiome, it triggers a biochemical cascade that enhances both structural skin integrity and the user's mood without any psychoactive compounds.

Neuro-cosmetic modulator Antioxidant Prebiotic Anti-inflammatory Skin conditioner

Science

This extract functions as a prebiotic that guides the skin's microbiota to produce a postbiotic cocktail, which in turn stimulates keratinocytes to synthesize oxytocin. This 'happiness molecule' communicates with sensory neurons to activate the brain's pleasure centers while simultaneously upregulating NRF2 antioxidant defenses and suppressing NF-κB-driven inflammatory pathways.


Research

High confidence
Effective range 1–3%
Optimal

2%

Key findings

  1. 01 At 1% concentration, 88% of users observed a visible reduction in wrinkles, with surface area decreasing by up to 44% over 28 days.
  2. 02 A 2% concentration demonstrated significant 'neuro-well-being' effects, with volunteers reporting increased confidence and relaxation via the Microbiota-Skin-Brain Axis.
  3. 03 A 3% concentration achieved a 94% improvement in skin firmness and a 95% acceleration in cellular renewal cycles.
  4. 04 In-vitro analysis confirmed significant antioxidant scavenging (19.39% DPPH) and suppression of pro-inflammatory cytokines IL-6 and IL-8.

Transparency

Commonly dusted
Min. effective
1%
Red flag below
0.1%

Because it is a high-tech 'story' ingredient associated with cannabis, brands often include it at trace amounts (below 1%) to claim the benefits of neuro-cosmetics without providing the 1-3% required for the clinically proven oxytocin-stimulating effects.


The Formula

Solubility
Both
Optimal pH 2 – 8
0 7 14

Stability

Highly versatile and stable across a broad pH spectrum. To maintain the integrity of the lysate's bioactivity, it must be incorporated during the cool-down phase at temperatures below 40°C.

Synergies

  • Probiotics
  • Adaptogens
  • Hyaluronic Acid
  • Niacinamide

Safety

CIR Status
Not reviewed
Max tested
3%
Pregnancy
Safe
Sensitization risk Low

Completely free from THC and CBD, making it globally compliant and safe for all users, including those avoiding cannabinoids.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Valuable

An innovative, multi-functional active that provides measurable structural anti-aging benefits while uniquely addressing the biological impact of stress on the skin.


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References