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CALOPHYLLUM TACAMAHACA FRUIT OIL.

Valuable CAS 223748-12-7 / SKIN CONDITIONING - EMOLLIENT

Commonly known as Tamanu oil, this dense botanical lipid is a potent regenerative agent that transcends basic emollience. It is specifically utilized in precision skincare for its unique ability to accelerate dermal repair and provide biological protection against UV-induced cellular damage.

Regenerative agent Biological UV filter Anti-inflammatory Antimicrobial Emollient

Science

This oil operates through a complex tripartite chemistry: calophyllic acid drives tissue regeneration, calophyllolide provides localized anti-inflammatory action, and inophyllum acts as a natural antimicrobial. At the cellular level, it stimulates the proliferation of keratinocytes and fibroblasts while upregulating the synthesis of collagen and glycosaminoglycans, effectively rebuilding the skin's structural matrix.


Research

High confidence
Effective range 5–100%
Optimal

20%

Key findings

  1. 01 Application of a 20% concentration demonstrated complete wound closure within 12 days without scar formation in vivo.
  2. 02 Topical use of 100% pure oil significantly diminished the appearance and size of established scars older than one year.
  3. 03 Exhibited biological UV-absorbing properties equivalent to SPF 18-22, effectively inhibiting DNA damage in skin cells.

Transparency

Not commonly dusted
Min. effective
5%
Red flag below
1%

While many oils are used at 0.1-1% for marketing, the regenerative data for Tamanu oil is concentrated between 5% and 20%. Formulations using it below 1% are likely leveraging it for basic emolliency rather than its clinically validated scar-reduction or healing benefits.


The Formula

Solubility
Oil
Optimal pH 4 – 7
0 7 14

Stability

Highly sensitive to photo-oxidation and thermal degradation; must be housed in opaque, airtight packaging. Contains natural resins that offer mild preservation, but the unsaturated fatty acid profile requires stabilization with antioxidants like Tocopherol.

Synergies

  • Vitamin E
  • Hyaluronic Acid
  • Ceramides

Conflicts

  • Strong oxidizing agents
  • High pH alkaline environments (neutralizes calophyllic acid)

Safety

CIR Status
Safe as used
Max tested
100%
Pregnancy
Safe
Sensitization risk Low

Generally non-toxic and well-tolerated. It is classified under the broad safety umbrella of plant-derived fatty acid oils by the CIR Expert Panel.


Your Skin

Yes Normal
Yes Dry
No Oily
Yes Sensitive
Irritancy Low
Comedogenicity Moderate

Our Assessment

Valuable

An exceptional therapeutic lipid for barrier repair and scar management, though its moderate comedogenicity requires careful selection for acne-prone skin.


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References