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CALLICARPA MACROPHYLLA FRUIT EXTRACT.

Valuable / SKIN CONDITIONING

Derived from the Large-leaf Beautyberry, this botanical extract bridges ancient Ayurvedic tradition with modern cellular science. It serves as a potent multi-functional active that targets pigment correction and provides robust oxidative protection for stressed skin.

antioxidant skin conditioning brightening repairing

Science

This extract operates via a dual-pathway approach: it inhibits tyrosinase activity and suppresses the MITF (microphthalmia-associated transcription factor) gene to downregulate melanin production. Additionally, its high concentration of carnosol and callicarpone flavonoids neutralizes free radicals and prevents the oxidative degradation of other sensitive actives like Vitamin C.


Research

Medium confidence
Effective range 0.1–5%
Optimal

0.5%

Key findings

  1. 01 In vitro analysis confirms that concentrations as low as 0.1% to 0.5% provide significant tyrosinase inhibition and DPPH radical scavenging (IC50 ~0.3 mg/mL).
  2. 02 A clinical pilot study demonstrated that a 5.0% concentration significantly accelerates wound contraction and fibroblast proliferation, facilitating tissue repair.

Transparency

Commonly dusted
Min. effective
0.1%
Red flag below
0.05%

Many mass-market formulations include Beautyberry at trace levels (<0.05%) for marketing claims. To achieve measurable brightening and antioxidant stability, a minimum threshold of 0.1% is required, with 0.5% being the Moumoujus-recommended precision dose.


The Formula

Solubility
Water
Optimal pH 4.5 – 6.5
0 7 14

Stability

Highly stable in aqueous solutions but vulnerable to thermal degradation and UV exposure. Should be housed in opaque or UV-protected packaging to maintain polyphenol integrity.

Synergies

  • L-Ascorbic Acid (Vitamin C)
  • Ferulic Acid
  • Niacinamide

Conflicts

  • Strong oxidizing agents
  • Highly alkaline formulations (pH > 8.0)

Safety

CIR Status
Not reviewed
Pregnancy
Safe
Sensitization risk Low

Recognized as a low-hazard botanical with no known systemic toxicity or irritancy at standard cosmetic use levels.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Valuable

An excellent botanical secondary active that excels at stabilizing Vitamin C and providing gentle, gene-level pigment regulation.


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