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CALCIUM XYLENESULFONATE.

Valuable CAS 28088-63-3 / SURFACTANT - CLEANSING, SURFACTANT - HYDROTROPE

A high-performance hydrotrope and coupling agent used to enhance the solubility of organic compounds in aqueous solutions. It acts as a structural stabilizer, ensuring that complex cosmetic formulations remain clear and homogeneous even under temperature fluctuations.

Hydrotrope Surfactant Viscosity Regulator Solubilizer

Science

It functions by disrupting the local structure of water to facilitate the dissolution of poorly water-soluble ingredients. By acting as a cloud-point depressant, it prevents phase separation in surfactant systems and regulates the viscosity of the final product without the need for high-viscosity polymers.


Research

High confidence
Effective range 0.5–5%
Optimal

2.5%

Key findings

  1. 01 Human Repeat Insult Patch Test (HRIPT) at 0.5% demonstrated no evidence of skin sensitization or irritation.
  2. 02 OECD SIDS evaluations confirm the ingredient is non-mutagenic and lacks systemic toxicity at consumer-relevant exposure levels.

Transparency

Not commonly dusted

As a functional stabilizer rather than a bioactive 'hero' ingredient, it is rarely used for marketing claims. Its inclusion is typically driven by formulation necessity rather than label-appeal.


The Formula

Solubility
Water
Optimal pH 7 – 9.5
0 7 14

Stability

Highly stable in neutral and alkaline environments; it is hygroscopic in nature and prevents precipitation at low temperatures.

Synergies

  • Anionic surfactants
  • Organic active ingredients
  • Non-ionic surfactants

Conflicts

  • Strongly acidic environments
  • Strong oxidizing agents
  • Cationic surfactants in high-load concentrations

Safety

CIR Status
Safe as used
Max tested
5%
Pregnancy
Safe
Sensitization risk Low

The CIR Expert Panel supports its safety in cosmetics when formulated to be non-irritating. OECD data confirms it is non-teratogenic.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Valuable

An essential technical component for stabilizing surfactant-based formulas and ensuring the uniform delivery of active ingredients.


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