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CALCIUM SULFATE HYDRATE.

Valuable CAS 13397-24-5 / ABRASIVE, ANTICAKING, ASTRINGENT, BINDING, BLEACHING, OPACIFYING, SKIN CONDITIONING

A multifunctional mineral compound used primarily for its structural properties in professional-grade facial masks. It undergoes a unique phase transition upon hydration to create a physical occlusive barrier that optimizes the delivery of concurrent active ingredients.

Astringent Occlusive Agent Mechanical Exfoliant Binding Agent Opacifier

Science

Functioning as both an astringent and a structural setting agent, this mineral facilitates an exothermic reaction when combined with water, converting from a hemihydrate to a dihydrate matrix. This process generates a mild, localized increase in skin temperature and creates an occlusive seal, which significantly enhances the skin's permeability and absorption of co-formulated nutrients.


Research

High confidence
Effective range 10–40%
Optimal

20%

Key findings

  1. 01 Clinical evaluation at 20.0% concentration using Finn chambers demonstrated zero irritation potential across test subjects.
  2. 02 Studies on alginate-based delivery systems confirm its role as a primary setting agent that maintains an occlusive environment for improved ingredient penetration.

Transparency

Not commonly dusted
Min. effective
5%
Red flag below
1%

In performance skincare, this ingredient is typically used at high concentrations (10-40%) to achieve its structural and occlusive benefits. Usage below 1% generally indicates a secondary role as an anti-caking agent or opacifier rather than a functional skin-delivery tool.


The Formula

Solubility
Water
Optimal pH 5 – 8
0 7 14

Stability

Exhibits retrograde solubility, becoming less soluble as temperature rises. Highly stable in its dry, powdered state but reacts rapidly with water to form a solid mass.

Synergies

  • Alginates
  • Humectants
  • Hydrating Polymers

Conflicts

  • Peptides
  • Amino acids
  • Amines
  • Proteins
  • Tetracycline antibiotics

Safety

CIR Status
Safe as used
Pregnancy
Safe
Sensitization risk Low

Classified as Generally Recognized as Safe (GRAS) by the FDA; clinical data confirms it is non-sensitizing and non-irritating in cosmetic applications.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Valuable

An essential mineral for professional occlusive treatments and texture refinement, offering high safety and significant absorption-boosting benefits.


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